Protein Info for GFF4288 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: AroM protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 225 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF07302: AroM" amino acids 5 to 224 (220 residues), 245.4 bits, see alignment E=2.3e-77

Best Hits

Swiss-Prot: 78% identical to AROM_SHIFL: Protein AroM (aroM) from Shigella flexneri

KEGG orthology group: K14591, protein AroM (inferred from 99% identity to seg:SG0402)

Predicted SEED Role

"AroM protein" in subsystem CBSS-562.2.peg.5158 SK3 including

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (225 amino acids)

>GFF4288 AroM protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MSASLAILTIGVVPMSEVLPLLTEYIDEQHITHHSLLGKMSREDVMADYAVEPGDDPLLT
LLNDNQIAHVSRQKVERDLQSVVEVLDNQGYDVIILMSTAAIKSMAARNSILLEPLRIIP
PLVASIVDGHQVGVIVPVAELLAAQEKKWQVLQMPPVYSLANPVHGSEQQLIDAGQALLD
QGADVIMLDCLGFHQRHRDILQQALDVPVLLSNVLIARLASELLV