Protein Info for GFF4268 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 16 to 39 (24 residues), see Phobius details amino acids 49 to 70 (22 residues), see Phobius details amino acids 79 to 97 (19 residues), see Phobius details amino acids 103 to 125 (23 residues), see Phobius details amino acids 139 to 160 (22 residues), see Phobius details amino acids 169 to 192 (24 residues), see Phobius details amino acids 221 to 248 (28 residues), see Phobius details amino acids 260 to 279 (20 residues), see Phobius details amino acids 287 to 304 (18 residues), see Phobius details amino acids 310 to 334 (25 residues), see Phobius details amino acids 351 to 368 (18 residues), see Phobius details amino acids 374 to 395 (22 residues), see Phobius details PF07690: MFS_1" amino acids 22 to 239 (218 residues), 46.3 bits, see alignment E=2.8e-16 amino acids 271 to 400 (130 residues), 50.1 bits, see alignment E=2.1e-17

Best Hits

KEGG orthology group: None (inferred from 75% identity to axy:AXYL_01660)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>GFF4268 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MTDTVTPSNGRRDARVLAICQGLYTAAVSIDLTLTALTGHMLAPDKSLATLPFALITVAG
AVVTWFASLLMQRIGRRGGFALGALAGTAGGLVSLWAVFHDDFWVFCAGTALVGVYQAFA
QFYRLAAADGVAAADKSRAVSTVLAGGVIAAIAGPALAAWSKDLFPPVLFAGAYLMVAVL
GAISVVLIVALYRDTQVQAAASGPVDTRPARPLGEIARQPIFIAALANNVVGSVSMMFVM
TAAPLAAVACSHSIDDGAGIMQWHLVGMYAPALFAGALIQRWGLPRVVSLGMVLNVVCSV
VAMSSTTLPAFYAALFCLGVGWNFMFVGGTTLLAQSYRPQERGRAQGAAELLRNVCTAGA
TLAAGPALDHFGWAPLNAAMLPVVLLAAVMTFVWARSARPATAGA