Protein Info for GFF4254 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: putative Cytochrome bd2, subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 transmembrane" amino acids 13 to 36 (24 residues), see Phobius details amino acids 55 to 76 (22 residues), see Phobius details amino acids 96 to 119 (24 residues), see Phobius details amino acids 126 to 147 (22 residues), see Phobius details amino acids 184 to 207 (24 residues), see Phobius details amino acids 219 to 236 (18 residues), see Phobius details amino acids 322 to 345 (24 residues), see Phobius details amino acids 357 to 377 (21 residues), see Phobius details amino acids 406 to 428 (23 residues), see Phobius details PF01654: Cyt_bd_oxida_I" amino acids 8 to 436 (429 residues), 571.8 bits, see alignment E=3.5e-176

Best Hits

KEGG orthology group: K00425, cytochrome bd-I oxidase subunit I [EC: 1.10.3.-] (inferred from 100% identity to seg:SG0371)

MetaCyc: 75% identical to cyanide insensitive ubiquinol oxidase subunit I (Pseudomonas putida KT2440)
RXN-6883 [EC: 1.10.3.11]

Predicted SEED Role

"putative Cytochrome bd2, subunit I" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 1.10.3.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (467 amino acids)

>GFF4254 putative Cytochrome bd2, subunit I (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MEFDAFFLARLQFAFTVSFHIIFPAITIGLASYLVVLEGLWLKTRNPVWRSLYQFWLKIF
AVNFGMGVVSGLVMAYQFGTNWSGFSQFAGSITGPLLTYEVLTAFFLEAGFLGVMLFGWN
KVGPGLHFLSTCMVALGTLMSTFWILASNSWMHTPQGFEIHNGQVVPVDWFAVIFNPSFP
YRLLHMSVAAFLSSAMFVGASAAWHLLKGNDTPAIRRMFSMALWMAVVVAPVQALIGDMH
GLNTLKHQPVKIAAIEGHWENTPGEPTPLTLVGWPDMEAERTRYALEIPALGSLILTHSL
DKQVPALKDYPKEDRPNSTVVFWSFRLMVGMGVLMIFLGLASLWLRYRRRLYHSRPFMHF
ALWMGPSGLIAILAGWVTTEVGRQPWVVYGLLRTRDAVSAHSTLQMSISLLAFFVVYSLV
FGVGYIYMIRLIQKGPQPAETPTAETDGRPARPISAVGESLEQEKRE