Protein Info for GFF4253 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Type III restriction-modification system StyLTI enzyme res (EC 3.1.21.5)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 989 PF04851: ResIII" amino acids 7 to 228 (222 residues), 86.5 bits, see alignment E=3.9e-28 PF19778: RE_endonuc" amino acids 872 to 970 (99 residues), 32.8 bits, see alignment E=1.1e-11 PF08774: VRR_NUC" amino acids 875 to 969 (95 residues), 41.6 bits, see alignment E=2.4e-14

Best Hits

Swiss-Prot: 100% identical to T3RE_SALTY: Type III restriction-modification system StyLTI enzyme res (res) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01156, type III restriction enzyme [EC: 3.1.21.5] (inferred from 100% identity to set:SEN0341)

Predicted SEED Role

"Type III restriction-modification system StyLTI enzyme res (EC 3.1.21.5)" in subsystem Restriction-Modification System (EC 3.1.21.5)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.21.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (989 amino acids)

>GFF4253 Type III restriction-modification system StyLTI enzyme res (EC 3.1.21.5) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MNILLEELPHQEQALAAILASFTGIDHAQADHNHYANPLIKERYDDKANIDVKMETGTGK
TYVYTRLMYELHQKYGLFKFVLVVPTPAIKEGARNFITSDYARQHFSQFYENTRMELCTI
NAGDFKVKSGRKNFPAQLLSFTDASRRDSHTIQVLLINAQMLNSASMTRDDYDQTLLGGL
TSPVKGLQMTRPVVIIDEPHRFARDNKFYRAIQAIQPQMIVRFGATFPDIVEGKGKNKCV
RKDYYRRQPQFDLNAVDSFNDGLVKGIDIYYPNLPEEQANNRYIVDSVTAKKLILRRGSK
IAEVGVGENLADVDAGFEGSIEYAGSKMLSNDLELEAGMALVPGTFGASYQELIIQDAID
KHFDTEQANFLRSNEPENNAPRIKTLSLFFIDSIKSYRDDEGWLKVTFERLLKKKLTQLI
DDYQRKTLPREVEYLSFLQATLASLHSDNQNVHAGYFGEDRGSGDEAIQAEVDDILKNKE
KLLSFSDHHGNWETRRFLFSKWTLREGWDNPNVFVIAKLRSSGSESSKIQEVGRGLRLPV
DENGHRVHQEEWPSRLSFLIGYDEKAFASMLVDKINRDSKVQLNEQKLDEAMITLIVTER
QKVDPAFTELRLLKDLDDKKLINRSNEFKPSVTLNGETKSGFAWLLEFYPELTQARVRAD
RIRDNKPASRLRVRLRKENWEQLSSIWEQFSRRYMLQFERSGASLEQIAAEVLRDPALYI
RQKPSQVQQRLVSNEDNGRFEVAQREGELAASEFMAGMKYGHFLKQLALRTSLPVNVLHP
VLMAMLRDVLHGDSRYLSEISLDNMTRALQTRINAHFAQRHDYLPLDFQASTSVFDSTAR
QFREEISAEIVGKNVDENAIDDPRSLYQIPPLRYDSVDPELPLLKYDYPQQVSVFGKLPK
RAIQIPKYTGGSTTPDFVYRIERQDADSVYLLVETKAENMRVGDQVILDAQRKFFDMLRR
QNINVEFAEATSAPAVFSTINGLIEGKAN