Protein Info for GFF4252 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Type III restriction-modification system methylation subunit (EC 2.1.1.72)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 652 PF01555: N6_N4_Mtase" amino acids 129 to 448 (320 residues), 170.6 bits, see alignment E=5e-54 PF18273: T3RM_EcoP15I_C" amino acids 553 to 648 (96 residues), 101.7 bits, see alignment E=2.4e-33

Best Hits

Swiss-Prot: 100% identical to T3MO_SALTY: Type III restriction-modification system StyLTI enzyme mod (mod) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K07316, adenine-specific DNA-methyltransferase [EC: 2.1.1.72] (inferred from 100% identity to stt:t2507)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (652 amino acids)

>GFF4252 Type III restriction-modification system methylation subunit (EC 2.1.1.72) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MLKDNQKHNESVAPNSAFLSELQRALPEFFTADRYNEQGELIAKGGFDLARFERALKARN
IDELTSGYQIDFIGKDYAKKQAGEKSVTVIVPDVEHNTLAENKNSHNLFLTGDNLDVLRH
LQNNYADTVDMIYIDPPYNTGSDGFVYPDHFEYSDRALQDMFGLNDTELARLKSIQGKST
HSAWLSFMYPRLFLARKLLKDTGFIFISIDDNEYANLKLMMDEIFGEGGFVTNVMWKRKK
EISNDSDNVSIQGEYILVYAKTGQGALRLEPLSKEYIQKSYKEPTEQFPEGKWRPVPLTV
SKGLSGGGYTYKITTPNGTVHERLWAYPEASYQKLVADNLVYFGKDNGGIPQRVMYAHHS
KGQPTTNYWDNVASNKEGKKEILDLFGDNVFDTPKPTALLKKIIKLAIDKDGVVLDFFAG
SGTTAHAVMALNEEDGGQRTFILCTIDQALSNNTIAKKAGYNTIDEISRERITRVAAKIR
ANNPATNSDLGFKHYRFATPTQQTLDDLDSFDIATGHFINTSGQLAAFTESGFTDMINPF
SARGLGVPGGASGEETLLTTWLVADGYKMDIDVQTVDFSGYCARYVDNTRLYLIDERWGT
EQTRDLLNHIGTHQLPVQTIVIYGYSFDLESIRELEIGLKQLDQKVNLVKRY