Protein Info for PS417_21735 in Pseudomonas simiae WCS417

Updated annotation (from data): ABC transporter for L-Arginine, permease component 2
Rationale: Specific phenotype on L-Arginine. This gene is listed because other components of the arginine transporter are misannotated. (SEED_correct) (KEGG_correct)
Original annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 transmembrane" amino acids 15 to 42 (28 residues), see Phobius details amino acids 55 to 76 (22 residues), see Phobius details amino acids 88 to 109 (22 residues), see Phobius details amino acids 162 to 183 (22 residues), see Phobius details amino acids 196 to 216 (21 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 12 to 117 (106 residues), 76.5 bits, see alignment E=9.8e-26 PF00528: BPD_transp_1" amino acids 31 to 223 (193 residues), 66.1 bits, see alignment E=1.8e-22

Best Hits

Swiss-Prot: 49% identical to OCCM_RHIRD: Octopine transport system permease protein OccM (occM) from Rhizobium radiobacter

KEGG orthology group: K10023, arginine/ornithine transport system permease protein (inferred from 100% identity to pfs:PFLU4763)

MetaCyc: 36% identical to L-arginine ABC transporter membrane subunit ArtM (Escherichia coli K-12 substr. MG1655)
ABC-4-RXN [EC: 7.4.2.1]

Predicted SEED Role

"Arginine/ornithine ABC transporter, permease protein AotM" in subsystem Arginine and Ornithine Degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U7V2 at UniProt or InterPro

Protein Sequence (232 amino acids)

>PS417_21735 ABC transporter for L-Arginine, permease component 2 (Pseudomonas simiae WCS417)
MIFDYNVIWEAMPLYLGGLLTTLKLLAISLFFGLLAALPLGLMRVSKQPIVNGAAWLYTY
VIRGTPMLVQLFLIYYGLAQFEAVRESFLWPLLSSATFCACLAFAINTSAYTAEIIAGSL
KATPNGEIEAAKAMGMSRYKLYRRILLPSALRRALPQYSNEVIMMLQTTSLASIVTLIDI
TGAARTVNAQFYLPFEAYITAGVFYLCLTFILVRLFKLAERRWLSYLAPRKH