Protein Info for GFF4240 in Variovorax sp. SCN45

Annotation: Integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 573 transmembrane" amino acids 21 to 45 (25 residues), see Phobius details amino acids 51 to 73 (23 residues), see Phobius details amino acids 84 to 105 (22 residues), see Phobius details amino acids 113 to 134 (22 residues), see Phobius details amino acids 143 to 159 (17 residues), see Phobius details amino acids 171 to 193 (23 residues), see Phobius details amino acids 202 to 225 (24 residues), see Phobius details amino acids 245 to 269 (25 residues), see Phobius details amino acids 290 to 308 (19 residues), see Phobius details amino acids 314 to 334 (21 residues), see Phobius details amino acids 341 to 358 (18 residues), see Phobius details amino acids 364 to 381 (18 residues), see Phobius details amino acids 402 to 424 (23 residues), see Phobius details amino acids 464 to 482 (19 residues), see Phobius details amino acids 491 to 530 (40 residues), see Phobius details amino acids 546 to 572 (27 residues), see Phobius details PF03169: OPT" amino acids 32 to 563 (532 residues), 102.4 bits, see alignment E=1.4e-33

Best Hits

KEGG orthology group: None (inferred from 64% identity to reh:H16_B2556)

Predicted SEED Role

"FIG00975736: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (573 amino acids)

>GFF4240 Integral membrane protein (Variovorax sp. SCN45)
MLPAQAPRKIRRRWLPAEGSWRYHLLLVVSGALVLGPLAGVTAAYMNFSLGFFVGGQVFA
GLLGSAVTAGYGANGRHGANYIQTAAASVAAMSGLGVLLQAMAWMGMPQPPAWHLVLYLA
CIGMFGAGVGMLYTPVLVERMRLTYPSGLAVANILRALTDPALLRRSVKQLGGGMGIGLV
TGLATARLAVLGTIGMSASTFGAGLVVGARIGVPAVTGGLVGLALKPWFVSAGWLQADDP
PRKVMFLIALGTIMGAAILDMALIFWRALPGVRRQATPDDAPRPAATHRLVLWVLFWGAA
TVACGHWLLAQPVFYLVVAVALVFVFALVNGISVGVSDSNPISSAFVVTVVILAALGLRD
PTVGLMAGAVLLMATGVACDMQQDRSTGWRLGSSRALQFRYQVMGIVVGAVLAVVFARLF
MAAYPVLLQDQTVLKADQQPAGWTSAMTYKFVGVLRGLTDDVPYQRMAIGMGIAAGLVIE
SLRKWIRPRGFVLDAIVLPSPYALSFGGFVPLSASLWFGAGGVAGTLWAARAPQRGHAPQ
DMSSASLFGGGLIAGDALAAVGLGVASLLAAVA