Protein Info for PS417_21680 in Pseudomonas simiae WCS417

Annotation: succinylglutamate desuccinylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03242: succinylglutamate desuccinylase
  • amino acids 6 to 326 (321 residues), 394.7 bits, E=1.7e-122
• PF04952: AstE_AspA
  • amino acids 49 to 327 (279 residues), 269.6 bits, E=1.7e-84

Best Hits

Swiss-Prot: 95% identical to ASTE_PSEFS: Succinylglutamate desuccinylase (astE) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K05526, succinylglutamate desuccinylase [EC: 3.5.1.96] (inferred from 95% identity to pfs:PFLU4751)

Predicted SEED Role

"Succinylglutamate desuccinylase (EC 3.5.1.96)" in subsystem Arginine and Ornithine Degradation (EC 3.5.1.96)

MetaCyc Pathways

• L-arginine degradation II (AST pathway) (5/5 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.96

Sequence Analysis Tools

See A0A1N7UG92 at UniProt or InterPro

Protein Sequence (334 amino acids)

>PS417_21680 succinylglutamate desuccinylase (Pseudomonas simiae WCS417)
MLALGKLLELTLAGREPAQKIQLTVDGVQMRWLSEGALEVRPPEAKDNGSDLLLSSGIHG
NETAPIELLDRLLHGIARGEIKPRTRILFLFGNPEAMRRGERYLELDVNRLFNGRHEKNI
GPEAMRAAELEQLARSFFSLPGRSRLHYDLHTAIRGSKIEQFALYPWKDGRQHSRHQLAR
LNAAGMQAVLLQNKTSITFTAFTYEQLDAEAFTLELGKARPFGQNQGVDVSRLETRLKQL
IEGTEPETESLDGLQLFAVSREVIKHSDAFLMHLPADVENFSPLAQGYLLAEDVAKTRWV
IEEEGARIIFPNPKVKNGLRAGILIVPTTEAGLA