Protein Info for GFF4194 in Pseudomonas sp. DMC3

Annotation: HTH-type transcriptional regulator GntR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 345 PF00356: LacI" amino acids 16 to 61 (46 residues), 61.6 bits, see alignment 1e-20 PF00532: Peripla_BP_1" amino acids 75 to 319 (245 residues), 78.1 bits, see alignment E=1.6e-25 PF13407: Peripla_BP_4" amino acids 75 to 276 (202 residues), 43 bits, see alignment E=8.5e-15 PF13377: Peripla_BP_3" amino acids 181 to 344 (164 residues), 104.2 bits, see alignment E=1.7e-33

Best Hits

KEGG orthology group: K06145, LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor (inferred from 93% identity to pfo:Pfl01_0249)

Predicted SEED Role

"Transcriptional regulator, LacI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (345 amino acids)

>GFF4194 HTH-type transcriptional regulator GntR (Pseudomonas sp. DMC3)
LNVEKPRKRRGAGRVTLNAVARAAGVSAITVSRYFNQPEQVSPERRERIAAVVAELGYVP
NLVAGGLASARGKIVGMVIPNISGPIFANTIQGFSDTLSRHGYQLLLASSYFDIEQEENA
VRAFLGWSPAALVLTSHFHSEGTEKMLAEADIPVIETWDYQPEREPMQIGFSHFEVGVAA
ARHLLKKGYQRIAFVQNSAPGDFSALERRDGYAATVREAGREPWIFAPDADRAPFEAGKQ
AMDALMNASPRPDAIIFANDNLAAGGLLAGQRAGIKIPADCAVLGFGDYPFAEMLLPSLS
TIKPPALEIGVLAATRVLESLGVLPSDKVQRLNLLRCQVIERESI