Protein Info for GFF4184 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: ClpB protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 857 TIGR03346: ATP-dependent chaperone protein ClpB" amino acids 6 to 854 (849 residues), 1474.7 bits, see alignment E=0 PF02861: Clp_N" amino acids 17 to 68 (52 residues), 53.1 bits, see alignment 1.6e-17 amino acids 94 to 145 (52 residues), 44.8 bits, see alignment 6.2e-15 PF00004: AAA" amino acids 203 to 336 (134 residues), 50.1 bits, see alignment E=2.2e-16 amino acids 602 to 727 (126 residues), 41.3 bits, see alignment E=1.2e-13 PF17871: AAA_lid_9" amino acids 342 to 443 (102 residues), 119.8 bits, see alignment E=2.5e-38 PF07724: AAA_2" amino acids 596 to 760 (165 residues), 235.4 bits, see alignment E=2.1e-73 PF00158: Sigma54_activat" amino acids 600 to 738 (139 residues), 27.7 bits, see alignment E=1.1e-09 PF07728: AAA_5" amino acids 601 to 722 (122 residues), 48 bits, see alignment E=7.4e-16 PF10431: ClpB_D2-small" amino acids 766 to 845 (80 residues), 100.1 bits, see alignment E=3.3e-32

Best Hits

Swiss-Prot: 100% identical to CLPB_SALTI: Chaperone protein ClpB (clpB) from Salmonella typhi

KEGG orthology group: K03695, ATP-dependent Clp protease ATP-binding subunit ClpB (inferred from 78% identity to aha:AHA_4071)

MetaCyc: 97% identical to protein disaggregase ClpB (Escherichia coli K-12 substr. MG1655)
RXN185E-10

Predicted SEED Role

"ClpB protein" in subsystem Protein chaperones or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (857 amino acids)

>GFF4184 ClpB protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSIRPLLTSAGINAGQL
RTAIDQALSRLPQVEGTGGDVQPSSELVRVLNLCDKLAQKRGDNFISSELFVLAALESRG
TLTDLLKSAGATTANITQAIEQMRGGESVNDQGAEDQRQALKKYTVDLTERAEQGKLDPV
IGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLAL
DMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLK
PALARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELH
HHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRII
QLKLEQQALMKESDEASKKRLDMLNEELDDKERQYSELEEEWKAEKASLSGTQTIKAELE
QAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQSEGKTMRLLRNKVTDAEIAEVL
ARWTGIPVSRMLEGEREKLLRMEQELHSRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGS
FLFLGPTGVGKTELCKALANFMFDSDDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGG
YLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQERFGELDYGRMKEMVLGVVSQNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLQ
RLYKRLEERGYEIHISDEALKLLSANGYDPVYGARPLKRAIQQQIENPLAQQILSGELVP
GKVIRLEANDDRIVAVQ