Protein Info for GFF4180 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Ribosome hibernation protein YfiA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 112 TIGR00741: ribosomal subunit interface protein" amino acids 1 to 97 (97 residues), 119 bits, see alignment E=5.4e-39 PF02482: Ribosomal_S30AE" amino acids 4 to 91 (88 residues), 81.2 bits, see alignment E=3.9e-27

Best Hits

Swiss-Prot: 92% identical to YFIA_ECOL6: Ribosome-associated factor Y (yfiA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K05809, ribosome-associated inhibitor A (inferred from 94% identity to ctu:CTU_31860)

Predicted SEED Role

"Ribosome hibernation protein YfiA" in subsystem Ribosome activity modulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (112 amino acids)

>GFF4180 Ribosome hibernation protein YfiA (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKEPQGFIADATINTPNGH
LVASAKHEDMYTAINELINKLERQLNKVQHKGEARRATASVKDASFVEAEEE