Protein Info for GFF4177 in Pseudomonas sp. DMC3

Annotation: Lipid A 1-diphosphate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 60 to 85 (26 residues), see Phobius details amino acids 98 to 117 (20 residues), see Phobius details amino acids 170 to 199 (30 residues), see Phobius details amino acids 212 to 230 (19 residues), see Phobius details amino acids 236 to 256 (21 residues), see Phobius details PF01569: PAP2" amino acids 128 to 230 (103 residues), 32.3 bits, see alignment E=3.8e-12

Best Hits

KEGG orthology group: None (inferred from 96% identity to pfo:Pfl01_0266)

Predicted SEED Role

"Membrane-associated phospholipid phosphatase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (266 amino acids)

>GFF4177 Lipid A 1-diphosphate synthase (Pseudomonas sp. DMC3)
MNNPGLFQSRWNLGRLVLCNVVPLALLAFWLWPTGQMLCVIFDEWLFRSLNAPLASNPIW
LHIWAIASLRPFDIVVGLILLTLLIKGDWVFRAIDVRRAFFGFFSILLLMVVIRALFSKF
ADHMGWQHSSPSMVLEGAVHISDYFPHLEKTWELKDRSGQSFPGDHASVLLIWALFMGVF
SRTVGQFLTVWGLAVLFMLPRLVAGAHWGQDDYIGGVLLAVWALGWGYYTPFAYHAANFW
LKMTAPVFALLGKLPMVSRMSVVRSA