Protein Info for GFF4173 in Xanthobacter sp. DMC5

Annotation: HTH-type transcriptional regulator XynR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 PF09339: HTH_IclR" amino acids 35 to 87 (53 residues), 41.7 bits, see alignment 7.7e-15 PF01614: IclR_C" amino acids 110 to 273 (164 residues), 58.1 bits, see alignment E=8.7e-20

Best Hits

KEGG orthology group: None (inferred from 72% identity to xau:Xaut_2805)

Predicted SEED Role

"Transcriptional regulator, IclR family" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>GFF4173 HTH-type transcriptional regulator XynR (Xanthobacter sp. DMC5)
VAGGLKAPAAGAGGPEHPSGATPDATPESAGGTQSIERAVALLMLVGRAGAEGARLADLV
ASSGLSKPTVRRVLLALVRAGLVDQDEASRRYHVGPEAYVLGTLAAPRFGIHALALDGLS
RIARQSGDCAFLSVPRGAFSVCLHREEGTWPIRTHVLQAGDRHPLGIGAGGLAILAALPE
AEAARIIEANAAALAAYPGYSPDLLRGAMSDTRARGYALNPGLYVAGSWGIGVPVRGADG
RPLGALSLAAIESRLGAERQKELVPLLQREAAALEAKLGGSERGPPQRPARSMARPAS