Protein Info for GFF4169 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Outer membrane component of tripartite multidrug resistance system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 511 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 20 to 478 (459 residues), 373 bits, see alignment E=1.1e-115 PF02321: OEP" amino acids 74 to 264 (191 residues), 81.1 bits, see alignment E=4.8e-27 amino acids 296 to 476 (181 residues), 88.9 bits, see alignment E=1.9e-29

Best Hits

KEGG orthology group: None (inferred from 96% identity to bxe:Bxe_A1155)

Predicted SEED Role

"Outer membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (511 amino acids)

>GFF4169 Outer membrane component of tripartite multidrug resistance system (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTSQPLLSQLLRQAGTALCTISLVGCAVGPDFVKPDDRLAAVQLSPRADYAQAQETSAAN
FPSSWWTLFNDDVLADLQARAQAGNLNLQIASERIEQSRAQLGIASSLLLPSVGASAGYS
REALSEHGKFAALGAPTSASDFWQLGFDASWELDLWGRARRSREGAAAAFEATVYEREAA
RVALSAEVARTYLQLRGTQAQLDITRQNLEVADRTLRLAESRERNGVATRFETASARAQL
ATVEALVPELVQRRNTLMNALALLQGEEPRALDAQLLEAMPLPSLPSNVPVGLPSELAHR
RPDIQRAEAQLHAATAAIGVAKADFYPRIGLRGRVGVEAFEFNDLDSWDSRFFSVGPTVY
LPIFQGGRLKQRLALNEARQRTAAIAYRQTVLQAWHEVDNALDAWAAQQHRHAELLVSYE
QNKQALHAAERGYQEGAADYLNVLAAQRGVLASQTSLNASATNAALTLVNLYKSLGGGWD
PDALTSDRQAGGDAPLTTTASSATSPSKAGQ