Protein Info for GFF4163 in Variovorax sp. SCN45

Annotation: Phosphopentomutase (EC 5.4.2.7)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01676: Metalloenzyme
  • amino acids 3 to 392 (390 residues), 129.3 bits, E=9.4e-42
• TIGR01696: phosphopentomutase
  • amino acids 3 to 398 (396 residues), 414.6 bits, E=1.7e-128

Best Hits

Swiss-Prot: 55% identical to DEOB_AGRRK: Phosphopentomutase (deoB) from Agrobacterium radiobacter (strain K84 / ATCC BAA-868)

KEGG orthology group: K01839, phosphopentomutase [EC: 5.4.2.7] (inferred from 55% identity to ara:Arad_0353)

MetaCyc: 52% identical to phosphopentomutase (Escherichia coli K-12 substr. MG1655)
Phosphopentomutase. [EC: 5.4.2.7]; 5.4.2.7 [EC: 5.4.2.7]

Predicted SEED Role

"Phosphopentomutase (EC 5.4.2.7)" in subsystem Deoxyribose and Deoxynucleoside Catabolism (EC 5.4.2.7)

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleosides degradation (5/6 steps found)
• 2-deoxy-α-D-ribose 1-phosphate degradation (2/3 steps found)
• purine ribonucleosides degradation (4/6 steps found)
• superpathway of purine deoxyribonucleosides degradation (3/7 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway
• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.7

Protein Sequence (402 amino acids)

>GFF4163 Phosphopentomutase (EC 5.4.2.7) (Variovorax sp. SCN45)
MARAVVVILDSFGLGATPDADRFGDRGADTLGHIAQWCVDAGRPLQLPALARMGLPQAAH
AATGRWPAGIPRHARPHGAFGAARETSRGKDTPSGHWELMGCPVAFDWGYFKPAQDPAQS
VFPPELMRRWYAACQLEGSLCNRHMSGTDVLVRFGDAHVSTGWPICYTSSDSVFQVAAHE
AHFGLERLYRICEIAKPLFDEVGIARVIARPFAGTAGSYRRTGGRHDYTTPPPAPTLLDA
LVGAGREVHAVGKISDIFAGRGITHGYPAEGNAALCERTLEALAACPDGGLVFSNLVDFD
MLYGHRRDIAGYADALQAFDAFLPRLVSALEPGDLLAISADHGCDPTWPGTDHTREHVPL
LFFGWEVPHSLDLGVRGSFADLGQTLARHLRTAPLAHGVSCW