Protein Info for PS417_21295 in Pseudomonas simiae WCS417

Annotation: electron transfer flavoprotein subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 PF01012: ETF" amino acids 3 to 170 (168 residues), 144 bits, see alignment E=4.7e-46 PF00766: ETF_alpha" amino acids 190 to 270 (81 residues), 124.2 bits, see alignment E=1.7e-40

Best Hits

Swiss-Prot: 87% identical to ETFA_PSEAE: Electron transfer flavoprotein subunit alpha (etfA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03522, electron transfer flavoprotein alpha subunit (inferred from 97% identity to pfs:PFLU4676)

Predicted SEED Role

"Electron transfer flavoprotein, alpha subunit" in subsystem Acetyl-CoA fermentation to Butyrate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U0E6 at UniProt or InterPro

Protein Sequence (309 amino acids)

>PS417_21295 electron transfer flavoprotein subunit beta (Pseudomonas simiae WCS417)
MTILVIAEHDNKVLAPATLNTVAAAAKIGGDIHVLVAGQGAGAVAEAAAKIAGVSKVLNA
DNAAYAHQLPENVAPLVAELGKSYSHILAAATSNGKNILPRVAAQLDVDQISEIISVESA
DTFKRPIYAGNAIATVQSNASVKVITVRATGFDPVAAEGGSATVEAVAAAHDAGTSSFVG
EELAKSDRPELTAAKIVVSGGRGMQNGDNFKHLYALADKLGAAVGASRAAVDAGFVPNDM
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
AVPELEKLV