Protein Info for GFF4119 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Type II/IV secretion system protein TadC, associated with Flp pilus assembly

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 99 to 120 (22 residues), see Phobius details amino acids 127 to 145 (19 residues), see Phobius details amino acids 275 to 300 (26 residues), see Phobius details PF00482: T2SSF" amino acids 163 to 290 (128 residues), 43.6 bits, see alignment E=1.4e-15

Best Hits

Predicted SEED Role

"Type II/IV secretion system protein TadC, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (309 amino acids)

>GFF4119 Type II/IV secretion system protein TadC, associated with Flp pilus assembly (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSPLPLAVVALLLLALALALAAGVLLYQHAQRQTTAQVIQRALGENAAPAHTLPEDLAFL
RGSRWPVRWLESRLGRLLVADEDRRLIQQCGLSPVRAQLALLVSRAALAVGLPLLVLLGW
GDAGNSLLWSAAAFAIGFMGPKWLLKHRAARQCERVAHELPLFVDMLGLLQSVGLSLDQS
LQVIASDFQHVMPVLGAEVARSNRQYSQGRTREQAYQRMAGLHDNQHLIDFIALINQVDK
HGGAVQEPIRQFSERLRVHRKAGMKARIGKITVKMTVVMVTTLLPALVIVTAGPGFLAII
RSVGSLTGS