Protein Info for GFF4113 in Hydrogenophaga sp. GW460-11-11-14-LB1
Annotation: Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 77% identical to LGT_POLSJ: Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase (lgt) from Polaromonas sp. (strain JS666 / ATCC BAA-500)
KEGG orthology group: K13292, phosphatidylglycerol:prolipoprotein diacylglycerol transferase [EC: 2.-.-.-] (inferred from 79% identity to rfr:Rfer_1923)Predicted SEED Role
"Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-)" (EC 2.4.99.-)
KEGG Metabolic Maps
- Glycosphingolipid biosynthesis - ganglio series
- Glycosphingolipid biosynthesis - globo series
- Glycosphingolipid biosynthesis - lacto and neolacto series
- Lipopolysaccharide biosynthesis
- Puromycin biosynthesis
Isozymes
Compare fitness of predicted isozymes for: 2.-.-.-
Use Curated BLAST to search for 2.-.-.- or 2.4.99.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (267 amino acids)
>GFF4113 Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-) (Hydrogenophaga sp. GW460-11-11-14-LB1) MLQHPQIDPVALQIGPVAIHWYGLTYLLAFGLFMLLANARLRHPPFASVTQPPWTRRDVE DILFLGVLGVVAGGRIGYCLFYKPAYYLANPLEVFAVWQGGMSFHGGLLGVMLAMVWYAR SRQRPFMQVMDFVAPCVPTGLAAGRLGNFINGELWGRVADPSLPWGMVFRGAGDLPRHPS QVYQFLLEGLLLFVLLWFYARKEHARGQVSAVFLFGYGVFRFIAEFFREPDAHLGLLSLG MSMGQWLCVPMIVGGAFMWWWFGQRKA