Protein Info for GFF410 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: Lactate-responsive regulator LldR in Enterobacteria, GntR family
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 86% identical to LLDR_SHIFL: Putative L-lactate dehydrogenase operon regulatory protein (lldR) from Shigella flexneri
KEGG orthology group: K14348, GntR family transcriptional regulator, L-lactate dehydrogenase operon regulator (inferred from 96% identity to sea:SeAg_B3910)Predicted SEED Role
No annotation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (258 amino acids)
>GFF410 Lactate-responsive regulator LldR in Enterobacteria, GntR family (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) VIVMPKRLSDEIASRVRALIEEQNLEAGMKLPAERQLALQLGVSRNSLREALAKLVSEGV LVSRRGGGTFVRWQHETWSEQNIVQPLKMLMANAPDYSFDILEARHAIEASTAWHAAMRA TAADKEKIRLCFDATLSEDPDLASQADVRFHLAIAEASHNVVLLQTMRGFFDVLQSSVKQ SRQRMYLVPPVFSKLTEQHQAVMDAILDGNAEGARKAMMAHLSFVHTTIKRFDEDQARQA RITRLPGDHNEMTRENKS