Protein Info for PS417_20895 in Pseudomonas simiae WCS417

Annotation: molybdenum cofactor sulfurylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 PF02625: XdhC_CoxI" amino acids 12 to 76 (65 residues), 65.7 bits, see alignment E=2.8e-22 TIGR02964: xanthine dehydrogenase accessory protein XdhC" amino acids 19 to 249 (231 residues), 325.3 bits, see alignment E=1.3e-101 PF13478: XdhC_C" amino acids 107 to 248 (142 residues), 123 bits, see alignment E=1.1e-39

Best Hits

KEGG orthology group: K07402, xanthine dehydrogenase accessory factor (inferred from 96% identity to pfs:PFLU4594)

Predicted SEED Role

"XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase)" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U7G4 at UniProt or InterPro

Protein Sequence (279 amino acids)

>PS417_20895 molybdenum cofactor sulfurylase (Pseudomonas simiae WCS417)
MNNWISALADLQNRGEPCVLVTIIEELGSTPRNAGSKMVISAAQSFDTIGGGHLEYKAMQ
IARDMLVRGQQNTHLERFSLGASLGQCCGGVTVLLFEPMGQVQAQIAVFGAGHVGRALVP
LLASLPCRVRWIDSRDQEFPAHIPQGVRKIVSEEPVDEIADLPVGSYCIVMTHNHALDLE
LTAALLKRNDFAYFGLIGSKTKRVKFEHRLRDRGFDTAHLQRMRCPMGLTEVKGKLPVEI
AISIAGEIIATYNANFGQHTASAEPIAKLLPASRRSQAI