Protein Info for GFF4078 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Flagellar L-ring protein FlgH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF02107: FlgH" amino acids 44 to 217 (174 residues), 183.9 bits, see alignment E=1e-58

Best Hits

Swiss-Prot: 54% identical to FLGH2_BURTA: Flagellar L-ring protein 2 (flgH2) from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)

KEGG orthology group: K02393, flagellar L-ring protein precursor FlgH (inferred from 55% identity to bpd:BURPS668_A0243)

Predicted SEED Role

"Flagellar L-ring protein FlgH" in subsystem Flagellar motility or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (219 amino acids)

>GFF4078 Flagellar L-ring protein FlgH (Hydrogenophaga sp. GW460-11-11-14-LB1)
MRALAVLSLAAATVLGGCAIVPPVAPPLADAPLPPVQPPVRKGQSGGLFNPSSAWVLTND
SRAFRSGDVLTVILAETTQASKRSGTSLDKRSSMSAQPLSIAGKVLDTSIGLSADREFSG
GSSSTQQNALEGAITVVVHEVMANGLLRVSGEKSLWLNQGEEFIRLSGFVRSEDIDATNR
VSSQRIANARIAYSGTGTLADANSPGWLTRFFTSPWMPF