Protein Info for GFF4074 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: ClpB protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1364 transmembrane" amino acids 20 to 49 (30 residues), see Phobius details amino acids 168 to 186 (19 residues), see Phobius details PF05488: PAAR_motif" amino acids 72 to 138 (67 residues), 58.7 bits, see alignment 1.3e-19 PF20148: DUF6531" amino acids 224 to 296 (73 residues), 76.4 bits, see alignment 4.5e-25 TIGR01643: YD repeat (two copies)" amino acids 497 to 538 (42 residues), 16.1 bits, see alignment (E = 1.3e-06) amino acids 582 to 620 (39 residues), 41.4 bits, see alignment (E = 1.3e-14) amino acids 625 to 663 (39 residues), 23.6 bits, see alignment (E = 5.6e-09) amino acids 666 to 706 (41 residues), 16.7 bits, see alignment (E = 8.2e-07) amino acids 731 to 768 (38 residues), 22.7 bits, see alignment (E = 1.1e-08) amino acids 1056 to 1094 (39 residues), 19.8 bits, see alignment (E = 8.7e-08) PF05593: RHS_repeat" amino acids 518 to 555 (38 residues), 29.9 bits, see alignment (E = 1.5e-10) amino acids 582 to 619 (38 residues), 45.5 bits, see alignment (E = 1.9e-15) amino acids 624 to 660 (37 residues), 37.4 bits, see alignment (E = 6.6e-13) amino acids 708 to 744 (37 residues), 24.3 bits, see alignment (E = 8.2e-09) amino acids 1056 to 1089 (34 residues), 25.2 bits, see alignment (E = 4.4e-09) PF03527: RHS" amino acids 1145 to 1177 (33 residues), 39.7 bits, see alignment (E = 9e-14) TIGR03696: RHS repeat-associated core domain" amino acids 1175 to 1251 (77 residues), 86.7 bits, see alignment 1.2e-28 PF24691: TreTu_C" amino acids 1253 to 1350 (98 residues), 143.4 bits, see alignment 7.9e-46

Best Hits

KEGG orthology group: None (inferred from 100% identity to stm:STM0291)

Predicted SEED Role

"ClpB protein" in subsystem Protein chaperones or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1364 amino acids)

>GFF4074 ClpB protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MYEAARVDDPIYHTSALAGFLIGAIIGIAIIALAAFAFFSCGFLAGLILGFMADQIASGV
LQLGEAIGRSIHHTAGKILTGSENVSTNSRPAARAVLSTVKCDNHIAEKRIAQGSENIYI
NSQPAARKDDHTECDAVIEDGSPNVFLGGGTQTVLEISSEIPDWLRKVVDVLFVVASLLG
GLAGAWRQAAKLGTKFGTKCAAKFIGGELVGMAVGEAISGLFSNPVDVTTGQKILLPETD
FTLPGRLPVTCSRFYASHLETVGLLGRGWRLNWETSLRDDDEHITLTGVQGRELRYPKTM
LTPGHQIFDPEEQLYLSRLHDGRYVLHYTDRSYYVFGDFDSDGMAYLLFMETPHRQRIVF
GHEGGRLVRIASSSGHHLLLHRTQTPAGERLSRIELVQGGTRGNLVEYRYDDNGQLTGVV
NRAGTQVRQFAYENGLMTAHSNATGFTCRYRWQELDGAPRVTEHDTSDGEHYRFDYDFAA
GTTTVTGRQGETWQWWYDRETYITAHRTPGGGMYRFTYNEDHFPVNIELPGGRTVAYEYD
IQNRVVKTTDPEGRVTQTQWNGEFDEITRTALDDDAVWKTQYNAHGQPVQETDPEGRVTQ
YAYDEQGQMCSRTDAAGGTVVTAFDSRGQMTRYTDCSGRSTGYDHDEDGNLTRVTDAEGK
VVRISYNRLGLPETVNSPGKQQDRYTWNALGLMSSHRRITGSVESWRYTPRGLLAAHTDE
EKRETRWQYTPEGRVAALTNGNGAQYRFSHDADGRLVREVRPDGLSRTFILDDSGYLTAI
QTTGTQGGVRRETQQRDALGRLLRTENEHGQRTFSYNRLDQITAVTLTPTEAGQQQHRMQ
ADTVRFEYDRSGWLTAEHAGNGSICYQRDALGNPTDITLPDGQHLTHLYYGSGHLLQTAL
DGLTVSEYERDSLHRQIMRTQGQLATYSGYDDDGLLSWQRSLASGSAPVLPGQRPARQGC
VTSRDYYWNNHGEVGTIDDGLRGSVVYSYDRSGYLTGRSGQMYDHDRYYYDKAGNLLDNE
GQGAVMSNRLPGCGRDRYGYNEWGELTTRRDQQLEWNAQGQLTRVISGNTETHYGYDALG
RRTRKATYGRHTGHTARSRTDFVWEGFRLLQENVQQQGWRTYLYDAEQPYTPVASVTGRG
ESRQVWYYHTDVTGTPQEVTAADGTLVWAGYIRGFGENAADISNSGAYFHQPLRLPGQYF
DDETGLHYNLFRYYAPECGRFVSQDPIGLRGGLNLYQYAPNPLKYIDPLGLTATVGRWMG
PAEYQQMLDTGTVVQSSTGTTHVAYPADIDAFGKQAKNGAMYVEFDVPEKSLVPTNEGWA
KIVGPDSIEGRLAKRKGLPVPEMPTAENITVRGEKINGEVEAKC