Protein Info for GFF4068 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: IcmF-related protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1289 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 44 to 63 (20 residues), see Phobius details amino acids 69 to 89 (21 residues), see Phobius details amino acids 97 to 117 (21 residues), see Phobius details amino acids 530 to 549 (20 residues), see Phobius details TIGR03348: type VI secretion protein IcmF" amino acids 68 to 1285 (1218 residues), 1021.5 bits, see alignment E=0 PF14331: IcmF-related_N" amino acids 265 to 538 (274 residues), 279.6 bits, see alignment E=3.6e-87 PF06761: IcmF-related" amino acids 590 to 915 (326 residues), 266.8 bits, see alignment E=4.4e-83 PF06744: IcmF_C" amino acids 1163 to 1268 (106 residues), 97.5 bits, see alignment E=7.4e-32

Best Hits

KEGG orthology group: K11891, type VI secretion system protein ImpL (inferred from 100% identity to stm:STM0285)

Predicted SEED Role

"IcmF-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1289 amino acids)

>GFF4068 IcmF-related protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MQKFLSLLFSRRALAVVGVLVLALLVWFVGPLVSFDTLRPLASVGSRVVTIALLLMLLVL
WLVNWSMSIIGISVLCLAIGFVTPLLALGDVHPFAPLWVRLTLIGFILLMYALYGLYRLW
RALRMDEQLLRRFLHPRGEEVPVAGEIKADLRTVNHIVTQAIRQLRQLRVDMPGWRKIFE
GKRFLYELPWFMVVGSPGDGKTTALLNTGLQFPLAEQMEQTSRILTVPGGGTLHCDWWFT
NEAVLIDTAGRYARHDDGGEASAAQRNAGEWQGFLGLLRKHRPGAPLNGVILTLNVADLT
AQSPAERLAACAALRARLAELRETLGIRFPVYLVVTKMDLLPGFSEYFRTLTSHLRAQIW
GFTLPYSRRRKAGDPQALHAACAQELARLTLRLDQGLDTRLQEEYDLKSRQRLYTFPREF
AALGEPLLEAIEQIFLDSKFDATQLNNTLRGVFFTSAAQAQADAVADQLSIWQRFVRAIK
TARGESSASLPHALPDGNRSYFLHDLLTQFIFREAHLVEPNLQWAWRYRLLRLGGHLLVL
VLAFLLWQGMQTSQQTNGDYLNEISARATRLDGDVKAYTGKPAMAPVPALLDSARELSAW
PELDPDAPPLAWRYGLYSVPPVTDSVASLYNRLLDQLLLPPLVKRMEYVLADAIARQDSK
AAYDALRIYLLLNLDKDHEDKYNAAEIQSWVINDLGNSDSVAGFGGRAAVLTHIEALFDG
SRVVHSPYEKDEALIRQARAFLDGHTSTERIYARALAAMESEAPQEFTLVRAVGADAGTV
FVRSNGAPLDRGVPGIFTREGYRELFDKRLPEFVAAATANDGWVMGRESTPKKLTDSLRS
QIPGQEQSVAREVRRLYLTEYARRWQDFLDSIHSINSAGEEGSSGLAYDLQVLRTLASPD
SPLMRLGKAVVEQTTLVPPPDPQARQKQLAQRASGNAGKVVQTAKLFQDIHPEERLEKTL
VDDRFAALREVIAGRTDGGQSGGGTMQIASLLTMLNEYYTQLTIADSALAAGTLPARITA
ADKLQLEAAKLPAPLKNILLDLTKQGTRKINAGTGDVLNTQMEAMMGDDCRDAIDGRYPF
ADSPQEVSAEDFNRIFASGGVLDAFWSKQLAPLADTASDPWRYKPTEGNMTLQGPDLTPF
QQAKQIRSVFFNSEGGKKFSWSMQISVVDMDPAIMELVIDIDGQVLRYAHGPDRPLKVTW
PGPRNGSMAEITASPRIRQDTSTLLTGGPWALFHLLDAGMVQETAVRGRQLVEYDFDGRR
VVLEITAGRDFNPVSRELLQNFSCPARAL