Protein Info for GFF406 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Transcriptional regulator, LacI family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 351 PF00356: LacI" amino acids 28 to 73 (46 residues), 57.4 bits, see alignment 1.9e-19 PF00532: Peripla_BP_1" amino acids 87 to 331 (245 residues), 81.4 bits, see alignment E=1.6e-26 PF13407: Peripla_BP_4" amino acids 87 to 329 (243 residues), 39.7 bits, see alignment E=8.7e-14 PF13377: Peripla_BP_3" amino acids 194 to 350 (157 residues), 80.5 bits, see alignment E=3.2e-26

Best Hits

KEGG orthology group: K06145, LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor (inferred from 99% identity to sec:SC3620)

Predicted SEED Role

"Transcriptional regulator, LacI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (351 amino acids)

>GFF406 Transcriptional regulator, LacI family (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MMNNARINQPIFAGASDVKRTKSPRAPTLEDVARSAGLSPMTVSRALNSPQLVRPKTVEK
VMQAVRVTGYIPNALAGGLASRRSKLIAVVVPQINNNMFVDTIQSLSDELARRGYHILLC
VAGYTEQTEAELVATLLSRRPDGVVLTGIHHTIELKKVILNAAIPVVEIWDLTPTPLDML
VGFSHEKVGQATGEYLLSKGYRRPGLLWTADRRAAQRKQGLCSVLQRHAIHAVPQVDVPL
PASLSLGRSGLSQLFDEGTFDVIVCSSDTLAQGAMMEAESRGLRIPHDLAVIGFGDLDFA
ASNRPSITTVSVDRRAIGQRAATLLADRIEQKPCAEAIVDIGFHLIGRESA