Protein Info for GFF4059 in Xanthobacter sp. DMC5

Annotation: Fosfomycin resistance protein AbaF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 transmembrane" amino acids 18 to 41 (24 residues), see Phobius details amino acids 53 to 76 (24 residues), see Phobius details amino acids 88 to 108 (21 residues), see Phobius details amino acids 115 to 141 (27 residues), see Phobius details amino acids 153 to 176 (24 residues), see Phobius details amino acids 187 to 206 (20 residues), see Phobius details amino acids 248 to 270 (23 residues), see Phobius details amino acids 276 to 296 (21 residues), see Phobius details amino acids 308 to 326 (19 residues), see Phobius details amino acids 332 to 351 (20 residues), see Phobius details amino acids 372 to 394 (23 residues), see Phobius details amino acids 400 to 425 (26 residues), see Phobius details PF00083: Sugar_tr" amino acids 20 to 231 (212 residues), 90.3 bits, see alignment E=1.3e-29 PF07690: MFS_1" amino acids 22 to 264 (243 residues), 56.7 bits, see alignment E=2.1e-19 amino acids 255 to 431 (177 residues), 55.7 bits, see alignment E=4.1e-19

Best Hits

KEGG orthology group: None (inferred from 72% identity to smd:Smed_4866)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (446 amino acids)

>GFF4059 Fosfomycin resistance protein AbaF (Xanthobacter sp. DMC5)
MAGQAGASSRELRRVVGASVIGATIEWYDFFLYGIVAGIVFNKLYFPADDPVISILLAYT
TFAVGFVARPVGGLIFGHFGDKLGRKSMLIITLMIMGVATVAIGLLPTYAQIGIAAPILL
LLLRVAQGIGIGGEWGGAVLMAYEYAPEDKRGFFASIPQIGLALGLCLASGVTAIVSMLP
DEQFMSWGWRVGFIGSIVLIIVGMYIRLKVHETPEFEQVKAANKAEAIPFITMLREYPRN
VLLGMGVRYIDGVFFNVFAVFSIVYLANYVKVPRTTALWLVTLAAFVMIFTIPMFGKLSD
KWGRPRTYAIGSALLALVVFPAFWLFSTGSLPLIALGIVFPFGVLYAMCYGPEAALFSDL
FDARVRYTGISFVYQFSGIVASGITPIIATYLLARGDGQPWQVCAYVVFAALVSMVSALA
IRVPVTRAQLSDARRTTPEAARQPAR