Protein Info for GFF4022 in Variovorax sp. SCN45

Annotation: UPF0060 membrane protein YnfA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 111 transmembrane" amino acids 7 to 28 (22 residues), see Phobius details amino acids 33 to 53 (21 residues), see Phobius details amino acids 60 to 78 (19 residues), see Phobius details amino acids 90 to 107 (18 residues), see Phobius details PF02694: UPF0060" amino acids 3 to 108 (106 residues), 137.4 bits, see alignment E=1e-44

Best Hits

Swiss-Prot: 78% identical to Y485_METFK: UPF0060 membrane protein Mfla_0485 (Mfla_0485) from Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)

KEGG orthology group: None (inferred from 77% identity to adn:Alide_2692)

Predicted SEED Role

"Protein of unknown function UPF0060"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (111 amino acids)

>GFF4022 UPF0060 membrane protein YnfA (Variovorax sp. SCN45)
MEVLKTLSLFVVTALAEIVGCYLPYLWLKQDRSAWLLVPAGIALALFAWLLSLHPAAAGR
VYAAYGGVYIGVAILWLWSVDGIRPTTTDWIGVAVSLAGMAIIMFGPRPTA