Protein Info for GFF4021 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 40 to 62 (23 residues), see Phobius details amino acids 74 to 93 (20 residues), see Phobius details amino acids 99 to 121 (23 residues), see Phobius details amino acids 133 to 153 (21 residues), see Phobius details amino acids 160 to 182 (23 residues), see Phobius details amino acids 214 to 234 (21 residues), see Phobius details amino acids 240 to 263 (24 residues), see Phobius details amino acids 283 to 309 (27 residues), see Phobius details amino acids 312 to 331 (20 residues), see Phobius details amino acids 340 to 360 (21 residues), see Phobius details amino acids 366 to 385 (20 residues), see Phobius details PF07690: MFS_1" amino acids 13 to 334 (322 residues), 74.7 bits, see alignment E=3.4e-25

Best Hits

KEGG orthology group: None (inferred from 89% identity to vpe:Varpa_1862)

MetaCyc: 36% identical to arsenic efflux major facilitator transporter ArsK (Agrobacterium tumefaciens GW4)
RXN-22376; RXN-22378; TRANS-RXN-454; TRANS-RXN0-551

Predicted SEED Role

"putative membrane protein"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (399 amino acids)

>GFF4021 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
VQSKTTTTVMLGLAQTLAWASSYYLPAVLAGAIGKDIGISMSTVFGAFSVALLVAAGIGP
FAGRLIDRLGGRPILIASNLVFAAGLAALSQASSTVHVFAAWALMGLAMGSGLYEAAFAT
VVRLHGQDARRAITGITLFAGFASTVGWPLSAYLESSVGWRGACLAWAALHLVIGLPLNV
LLPRASRTDQASKDATVVEKEVGSGLAPAQQRRAAFLMAYVFAVTWFISTAMAAHLPELL
LASGATLAAAVGIAALVGPAQVVGRVIEFTFLKRAHPLLSARLATLAHPLGALCLGLLGT
SAAAAFAVLHGLGNGILTIAIGTLPLMIFGAKGYGQRQGFLVVPARIVQAGAPFLFGMAV
ERWGDGALWFSALLGLSACFALVVMTMDMRKAPRAVEAH