Protein Info for PS417_20370 in Pseudomonas simiae WCS417

Annotation: haloacid dehalogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 PF00702: Hydrolase" amino acids 5 to 183 (179 residues), 43.9 bits, see alignment E=3.8e-15 TIGR01549: HAD hydrolase, family IA, variant 1" amino acids 65 to 183 (119 residues), 25.7 bits, see alignment E=6.5e-10 PF13242: Hydrolase_like" amino acids 137 to 201 (65 residues), 23.6 bits, see alignment E=3.9e-09

Best Hits

KEGG orthology group: None (inferred from 39% identity to psa:PST_3415)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U003 at UniProt or InterPro

Protein Sequence (218 amino acids)

>PS417_20370 haloacid dehalogenase (Pseudomonas simiae WCS417)
MPIVAAVFDAFGTVVHIRRKHHPFRKLLHIGAQQGRKPSVSGLHCLMTSSLSLERAAEVF
GIRLSSQQLMALQDDLLDELESISVYADAVEAQQLLKAEGMVMGVCSNLAAPYGPVLRHL
LNDMDGFALSYEVGLMKPHEGIYREICRQLGARLGSDLTTSGDKVVMVGDSLQCDQKGPR
AVGISGHFLDRTGAGSLSDLVQFAERVIKGKRLGESRG