Protein Info for GFF3947 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Fosmidomycin resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 57 to 79 (23 residues), see Phobius details amino acids 86 to 103 (18 residues), see Phobius details amino acids 109 to 131 (23 residues), see Phobius details amino acids 145 to 169 (25 residues), see Phobius details amino acids 175 to 193 (19 residues), see Phobius details amino acids 226 to 248 (23 residues), see Phobius details amino acids 260 to 285 (26 residues), see Phobius details amino acids 294 to 312 (19 residues), see Phobius details amino acids 318 to 336 (19 residues), see Phobius details amino acids 354 to 375 (22 residues), see Phobius details amino acids 381 to 401 (21 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 356 (331 residues), 139.8 bits, see alignment E=5.3e-45 amino acids 293 to 400 (108 residues), 38.7 bits, see alignment E=2.9e-14

Best Hits

KEGG orthology group: None (inferred from 72% identity to pol:Bpro_2824)

Predicted SEED Role

"Fosmidomycin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>GFF3947 Fosmidomycin resistance protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSSSSTTSTLPPVALRQDASLIGLVGLAHMVSHFSQLLLAPLFPWLKDAFNASYAELGFL
MTVFFVTSCAVQAASGFVVDRLGPRPVLFAGLALLGLAAFGFAASTHYWMMALFAVVAGI
GNGVFHPVDYTLLNRKVSAPRLGHAYSVHGITGSLGWALAPAMMVPIALAYSWRAALASA
GVLAFVVLAVLWFNRERLALPAAPKPAPGASQGAVENPMAFLRIPAVWMCFGFFFFYAMA
LSVVQAFAPEAARQLHGVPLALVAVCLTIYMVCSAGGMVLGGFLAADPARCERVVGVGFG
LAACIALVLAFAHVPAAAVPVLFGAMGFSAGIAGPSRDLLVKKSTPDNATGRVYGVVYSG
LDIGQAISPLIFGVLMDHGQFQGVLIGLAVVQAVLIASAFNVRRVRRTALVPA