Protein Info for GFF3912 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 806 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details PF07715: Plug" amino acids 63 to 176 (114 residues), 101.2 bits, see alignment E=4.7e-33 PF00593: TonB_dep_Rec" amino acids 328 to 755 (428 residues), 204.7 bits, see alignment E=4.9e-64

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 62% identity to spc:Sputcn32_3636)

Predicted SEED Role

"TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (806 amino acids)

>GFF3912 TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSRASTPSAGRRGVSSDYRFPLQATAVACSLYVMSLGVAHAQQAETTSLSEVVVSASGFE
QKITDAPASISVITQEELSRRPYVTLLDAVRDIEGVDVGETRDKTGQGTISMRGMGSDYT
LILVDGKRQNNHGDIYPNSFSGNQFGHVPPMDAIERIEVIRGPASTLYGADAMGGVINII
TKKVANKWSASVTHGRTFETKDEYGNDRTTDFYVSGPLVEGKLGLTLRGSLYNRDASNPI
YNSVTDPAGAVHDRSLGFGGGGKTVENENKALGARLSWALTDKQTVYVDVDTSRQTYDNR
IRINDAGVEEYPVGTVDSLAAIWTASGAGASRRANPRAGYAPEQEFTRDTFSVTHEGKWD
IGNSTVSLSHIATNNNGRTLPFGVEERKHLLAMIDSASYTAPDGTVSNYAGMTLAERQAA
ASSTFLPRPKRTLESRQYTLDGKLDMPFGDHMVVVGAQVIRGELEDGVFGMESGTPGGVQ
SHNMVSLFAEDSWNVIQPLVLTGGLRYDHHNVFGNQVSPRLYGVYTLNPNWTIKGGAATG
FKTPKTTQLYDGITGFGGQGTSPMYGNPNLKPETSLSNEVAVYWQDPRGHNFNATVFHNT
FDDKIASQPCGAGTSLVCATAGDFAELGYAAGSTRTTNIDKVVIQGVELAGRWQISRAFG
LRGNYTYTDSEQKSGVDRGKPLGNTAKHMFNASLDWQATDKLSFLLSAQAFMDRYRGQHV
ITNEALFYKDYHVFNLGASYKVSKNVTLNARINNLFDRDFTSYTSEFRDLNGNGVYQAGT
NEVLHYDDYNNKEKARSFWVSLNVRF