Protein Info for PS417_19960 in Pseudomonas simiae WCS417

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 127 transmembrane" amino acids 7 to 31 (25 residues), see Phobius details amino acids 37 to 56 (20 residues), see Phobius details amino acids 79 to 99 (21 residues), see Phobius details amino acids 102 to 120 (19 residues), see Phobius details PF04304: DUF454" amino acids 10 to 123 (114 residues), 147.3 bits, see alignment E=9.6e-48

Best Hits

Swiss-Prot: 45% identical to YBAN_SHIFL: Inner membrane protein YbaN (ybaN) from Shigella flexneri

KEGG orthology group: K09790, hypothetical protein (inferred from 98% identity to pfs:PFLU4470)

Predicted SEED Role

"Hypothetical protein DUF454" in subsystem Heme, hemin uptake and utilization systems in GramPositives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UL88 at UniProt or InterPro

Protein Sequence (127 amino acids)

>PS417_19960 membrane protein (Pseudomonas simiae WCS417)
MGNRSLLLRYGLLAIGWLSVALGVIGIFLPVLPTTPFLLLAAACFARSSPRFYHWLVQHP
RLGPWIRDYLDGNGIPLKGKVYAIGLMWLSISVSCYLVPLPWARGFMLTSAVLVTIYILR
QKTLPPR