Protein Info for GFF3877 in Variovorax sp. SCN45

Annotation: Uncharacterized chaperone protein YegD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 PF06723: MreB_Mbl" amino acids 93 to 202 (110 residues), 28.4 bits, see alignment E=7.8e-11 PF00012: HSP70" amino acids 99 to 232 (134 residues), 36.4 bits, see alignment E=2e-13

Best Hits

KEGG orthology group: K04046, hypothetical chaperone protein (inferred from 90% identity to vap:Vapar_1409)

Predicted SEED Role

"Putative heat shock protein YegD" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (426 amino acids)

>GFF3877 Uncharacterized chaperone protein YegD (Variovorax sp. SCN45)
LSVSSPSSLPTIGIDFGTSNSAVACRVDGAARLLPIEGAATTLPTAIFFNSEDRTTHFGR
DAIAQYLSGTEGRLMRSLKSLLGSALMQEKTAIYDGLVSFEDIIARFLRELAVRAGRELG
QLPERVVIGRPVHFVDDDPKRDERAEESLRVAARAAGFREIAFQLEPIAAAFDYEQRIAK
ESIVLIVDIGGGTSDFTVVRVGPDRAAREDRSDDVLATSGVHIGGTDFDQRLNLERVMPH
FGFRHHGPQGREVPSKVFFELSSWHLINWLYAAKAVRQAKELRTSYSDTRLHDRLMNVLE
ERHGHRIASAVEAAKIDASVTDAETAIDLDCAERGLVASLSPADMAQQLAGPLENVIACA
HACVKRAGLRSGDLDAIYLTGGSSALRPFQHALRKSFAGVNLVEGDLFGGVATGLACVAR
TARAAR