Protein Info for GFF3852 in Variovorax sp. SCN45

Annotation: Tetrapyrrole methylase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 PF00590: TP_methylase" amino acids 50 to 231 (182 residues), 42.9 bits, see alignment E=2.8e-15

Best Hits

KEGG orthology group: K07056, (no description) (inferred from 93% identity to vap:Vapar_1384)

Predicted SEED Role

"Tetrapyrrole methylase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (253 amino acids)

>GFF3852 Tetrapyrrole methylase family protein (Variovorax sp. SCN45)
VTHGKLYLVPAPLDFGCDTQAPLQDALPLGTLQAAAGITHWICENAKSARAYLKRIDAVT
PLAAPLQAQNIQELPREVHKKGDHAGQFDARPLLAAALEGHDIGLLSEAGMPAVADPGSS
VARAAHDLGLSVVPLTGPVSLLLALAASGLNGQNFAFVGYLPQDAVERQTRIRELEALAL
KSGQTQLFIETPYRNAALLQALIQTLQHNTRLAVARGLTLATAQVRSETVKSWRAKPQPT
TDERLPAVFAIGR