Protein Info for GFF3843 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 50 to 70 (21 residues), see Phobius details amino acids 78 to 101 (24 residues), see Phobius details amino acids 107 to 126 (20 residues), see Phobius details amino acids 138 to 161 (24 residues), see Phobius details amino acids 167 to 187 (21 residues), see Phobius details amino acids 199 to 217 (19 residues), see Phobius details amino acids 229 to 247 (19 residues), see Phobius details amino acids 268 to 289 (22 residues), see Phobius details amino acids 297 to 318 (22 residues), see Phobius details amino acids 330 to 350 (21 residues), see Phobius details amino acids 356 to 379 (24 residues), see Phobius details amino acids 401 to 420 (20 residues), see Phobius details amino acids 479 to 501 (23 residues), see Phobius details PF07690: MFS_1" amino acids 17 to 403 (387 residues), 176.3 bits, see alignment E=1.2e-55 PF00083: Sugar_tr" amino acids 46 to 183 (138 residues), 38.3 bits, see alignment E=1.2e-13 PF12832: MFS_1_like" amino acids 56 to 170 (115 residues), 35 bits, see alignment E=1.3e-12

Best Hits

KEGG orthology group: None (inferred from 80% identity to vpe:Varpa_1517)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (522 amino acids)

>GFF3843 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSLSHTGRNRVALAAISLIALMFGLEISSVPVILPTLEKELQGDFSDMQWIMNAYTIACT
TVLMAAGTLADRYGRKRILIIGIVLFGITSLICGLSQSAWLLIVSRFLQGLSGGAMLISQ
LAVLSHQFQQGKERSKAFAIWGVVFGMGLGFGPIVGGAIVALSNWQWVFLVHAPLAAVAL
ALVLGSVSESSDPDAQRLDLPGIVTLSLAVLGLTYFITQGPGIGFGSPLALGILGASAAS
FAVFVWVEIINPHPMFDFSVFRIRNFSGALIGSAGMNFSFWPFMIYLPIYFQGALGYDAV
TAGSALLAYTLPTLVMPPVAERMSLRWRPGVVIPLGLFVIGLGFMAMRLGSGMADASWIT
MLPGCLLAGIGLGLTHTPVTNTATGSVPSTRAGMASGMDMSARLITLAINIAVMGFILLE
GVHSHLKAALSASLDAPQLRALAEKVAAGSFASLGESFPVLSQVDPSGATVHAALMHSFG
WVMLFGAIGVWVLAGVSLLVFGNGRLPVPACGLKAAKESACS