Protein Info for PS417_19655 in Pseudomonas simiae WCS417

Annotation: chemotaxis protein CheW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 transmembrane" amino acids 116 to 136 (21 residues), see Phobius details PF01584: CheW" amino acids 114 to 246 (133 residues), 53.1 bits, see alignment E=1.4e-18

Best Hits

KEGG orthology group: K03408, purine-binding chemotaxis protein CheW (inferred from 93% identity to pfs:PFLU4408)

Predicted SEED Role

"CheW domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U6S0 at UniProt or InterPro

Protein Sequence (262 amino acids)

>PS417_19655 chemotaxis protein CheW (Pseudomonas simiae WCS417)
MNRPVELKTRPQLALESYLDALLQDATAQEFPEPILVLEPAVEPEAVLDEFQLAVLEEQA
RDARSVVPMTPQVAPVVVAPAVVEPVVEVHLPPSITPPPVAGDDRPSWAAEPFECLLFDV
AGLTLAVPLVCLGSIYSLEGQELTPLFGQPEWFLGILPSQAGNLKVLDTARWVMPDRYRD
DFRQGLQYVISVQGYEWGLAVHQVSRSLRLDPNEIKWRSHRGQRPWLAGTVIEHMCALLD
VAELAELIASGAVKAMPVNKRS