Protein Info for GFF3837 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: putative inner membrane efflux protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 63 (22 residues), see Phobius details amino acids 75 to 95 (21 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 133 to 154 (22 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details amino acids 212 to 232 (21 residues), see Phobius details amino acids 238 to 260 (23 residues), see Phobius details amino acids 272 to 288 (17 residues), see Phobius details amino acids 294 to 316 (23 residues), see Phobius details amino acids 338 to 371 (34 residues), see Phobius details PF07690: MFS_1" amino acids 14 to 267 (254 residues), 100.1 bits, see alignment E=1.3e-32 amino acids 212 to 387 (176 residues), 65.3 bits, see alignment E=5e-22 PF12832: MFS_1_like" amino acids 189 to 344 (156 residues), 32.5 bits, see alignment E=5e-12

Best Hits

KEGG orthology group: None (inferred from 66% identity to aaa:Acav_1952)

Predicted SEED Role

"putative inner membrane efflux protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (392 amino acids)

>GFF3837 putative inner membrane efflux protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
LNPQLRSVLWRLIAAQICLHACMTGFRMAAPLMALREGYSPVAVGVLLALFALAPVFMAL
PAGRYADRRGLRKPVMLSVGVASAGAALAVIFPVFPVLCLTALTCGAGTGMAMIALQRHV
GRLAHGPTELKQVFSWMAIGPSISNFLGPFAAGVMIDSFGFRAAFLLLALLPSLAWFGVR
HTVEHEPVAPELRKSSGSSWNLLKDKAFRQLMILNWMLSSCWDVHTFLVPVLGHERGLSA
TVIGTILGAFALAATAIRLLMPWLASHLRESVVIGSAMVATALLFAAYPLVHAAWAMGIL
SVLLGFALGSVQPMIMSSLHQMTPHHRHGEALGLRAMAINGSSVVMPLMFGSVGALIGVG
SVFWLVGSVVGLGSPLAWRLPAPTPEAPARQP