Protein Info for PS417_19545 in Pseudomonas simiae WCS417

Annotation: peptide synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 500 1000 1500 2000 2500 3000 3500 4000 4293 transmembrane" amino acids 77 to 95 (19 residues), see Phobius details amino acids 217 to 240 (24 residues), see Phobius details amino acids 914 to 926 (13 residues), see Phobius details amino acids 1948 to 1966 (19 residues), see Phobius details amino acids 2227 to 2235 (9 residues), see Phobius details PF00501: AMP-binding" amino acids 15 to 405 (391 residues), 234.9 bits, see alignment E=2.8e-73 amino acids 1127 to 1469 (343 residues), 317.6 bits, see alignment E=2.1e-98 amino acids 2170 to 2523 (354 residues), 264.9 bits, see alignment E=2.1e-82 amino acids 3692 to 4039 (348 residues), 241.5 bits, see alignment E=2.7e-75 PF00550: PP-binding" amino acids 581 to 642 (62 residues), 54.8 bits, see alignment (E = 1.8e-18) amino acids 1617 to 1679 (63 residues), 51.3 bits, see alignment (E = 2.2e-17) amino acids 2683 to 2743 (61 residues), 56.4 bits, see alignment (E = 5.8e-19) amino acids 4204 to 4267 (64 residues), 63.9 bits, see alignment (E = 2.6e-21) PF00668: Condensation" amino acids 664 to 1107 (444 residues), 377 bits, see alignment E=2.5e-116 amino acids 1705 to 2149 (445 residues), 345.3 bits, see alignment E=1.1e-106 amino acids 2764 to 3193 (430 residues), 261.2 bits, see alignment E=3.5e-81 amino acids 3221 to 3671 (451 residues), 306.9 bits, see alignment E=4.8e-95 TIGR01733: amino acid adenylation domain" amino acids 1143 to 1540 (398 residues), 442.6 bits, see alignment E=3.8e-136 amino acids 2191 to 2597 (407 residues), 413.5 bits, see alignment E=2.6e-127 amino acids 3713 to 4114 (402 residues), 407.1 bits, see alignment E=2.2e-125 PF13193: AMP-binding_C" amino acids 2581 to 2655 (75 residues), 49.9 bits, see alignment (E = 1e-16) amino acids 4098 to 4175 (78 residues), 36.2 bits, see alignment (E = 2e-12) TIGR01720: non-ribosomal peptide synthase domain TIGR01720" amino acids 3060 to 3213 (154 residues), 154.5 bits, see alignment (E = 6.2e-49)

Best Hits

Predicted SEED Role

"Pyoverdine chromophore precursor synthetase PvdL" in subsystem Siderophore Pyoverdine

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UF32 at UniProt or InterPro

Protein Sequence (4293 amino acids)

>PS417_19545 peptide synthase (Pseudomonas simiae WCS417)
MMDAFELPPTLVQSLQRRAAQTPDQVALRFLAESAEHSVVLSYRDLDQRARTIAAALQAN
ADLGDRAVLLFPSGPDYVAAFFGCLYAGVIAVPAYPPESTRRHHQARLLSIISDAEPRLL
LTIASLADGLSQLENAPPVLSVDRLEGAGNWVAPDLHPDDIAFLQYTSGSTALPKGVQVS
HGNLVANEVLIRRGFGIDLNPDDVIVSWLPLYHDMGLIGGLLQPIFSGVPCVLMSPAYFL
GRPLRWLEAISEYGGTISGGPDFAYRLCSERVSETALERLDLSRWRVAYSGSEPIRLDTL
ERFAEKFAACGFTPNHFFASYGLAEATLFVAGGSRGQGIAAMRVDDQALAANRAEPGQGS
AIMSCGTRQPEHAVLIADPHTLAELPDNHVGELWATGPSIAHGYWRNPEATAKTFVQHAG
RRWLRTGDLGFIRDGEVYITGRLKDLLIVRGHNLYPQDIEQTIEREVEVVRKGRVAAFAV
NEQGLEGIGIAAEISRSVQKILAPEALIKAIRQAVAEAYQEAPSVVVLLNPGALPKTSSG
KLQRAACGLRHKDGSLDSYAQFPNLHAQEGDGALESELHNQIAAIWCEQLQVATVAADDH
FFLLGGNSITATQVVARLRESLGLELNLRMLFEAPTLEGFAASVAQLQQDGGVAQGAIHS
LSRQEELPQSLAQSRLWITWQLDPHSSAYTIPGALRLRGELDEDAVRTSFQQLIQRHEAL
RTRFYERDGQAFQRVDTKADFDLQVIDLSDLPVAEREARAQQIREDEARTQFDLEKGPLL
WVTLVRLDDEDHQLLVTLHHIIADGWSLNILMDEFSRLYAAAVQGQTLELPPLALQYADY
GTWQRQWLAEGEGQRQLAYWKAQLGEEHPTLSLATDHPRSVHHRHSASRHTVRLGASLSE
AIRQTARTHESTPFMLLLAAFQSVLYRYSGQRDIRIGVPNANRPRQETQGLVGFFINTLV
LRAELDGRLPFTELLAATRQAALGAQAHQDLPFEQLLEAFPQAREQGLFQVMFNHQQRDL
SALRRLPGMLADELPWHSREAKFDLQLHTEEDRNGRLSLSFDYADELFESATIQRLAEHY
INLLHAICEQPRQAIGDLMLMQHDEQALYSEAPCAPAQVWLPELLNQQTSDTTALVWDGG
SLTFAQLHTQANRLAHYLRDKGVGPDVCVAIAAERSPQLLIGLLAIIKAGGAYVPLDPDY
PTERLAYMLKDSGVHLLLTQTALLEQVPAACGVCVIAMDSLHLDSWPTQPPGLHLHGDNL
AYVIYTSGSTGQPKGVGITHAALAERLQWMQATYPLNETDVLMQKAPISFDVSVWECFWP
LITGCRLVLAGPGEHRDPHRIAQLVQEHGVTTLHFVPPLLQLFIDEPLVAECTSLRRLFS
GGEALPAELRNRVLAQLPAVQLHNRYGPTETAINVTHWHCRAEDGERSPIGRPLGNVICR
VLDEQLNPVPLGVPGELCIGGIGLARGYLGRAGLTAERFVADHQGARLYRTGDRARWSAD
GVIEYLGRLDQQVKLRGFRVEPEEIEARMLALEGIAQAVVLVRDGQLIGYFTAHGDLDEQ
QVKTALAAELPEYMVPALLMRLDAMPLSPSGKLDRRALPEPVWQVREHVEPETPLQQQIA
AIWREVLGLPSIGLRDDFFALGGHSLLATQIISRTRQACDVELPLRTLFDASELGAFAEQ
VGLIQASGQRNQQTVIAKVDRGQPVPLSYSQQRMWFLWQMEPDSPAYNVGGMARLRGVLD
VGRFEAALQALIMRHETLRTTFPSVDGVAYQNVSPQTGLRMDWQDFSALSEADRQPRLQR
LADHEAHTPFNLETGPLLRACLVKAGEQEHYLVLTLHHIVTEGWAMDIFARELSALYEAF
IDERDSPLAPLPVQYLDYSVWQRQWLESGERQRQLDYWTAQLGNEHPLLELPGDRPRPPV
QSHQGELYRFDLSDDLAARVRAFNAERGLTLFMTMTATLAVLLYRYSGQTDLRIGAPVAN
RIRPESEGLIGAFLNTQVLRCQLNGQMNVAELFEHVRHTVIEGQSHQDLPFDHLVEALQP
PRSAAYNPLFQVMCNVQRWEFQQSRQLAGMTVEYLANDARATKFDLNLEVTDLDHRLGCC
LTYSTDLFDEPRIARMAAHWRNLLEALIADPQQRLSELPLLGADEQRVLQDSLGIENGEH
RLDQCIHPLFSQQVAVRGDAPALTFAGVTLSYRELDARANRLAWMLRERGVGPQVRVGLA
LPRSLEMVIGLLAILKAGGAYVPLDPEYPLDRLHYMIEDSGIGLLLSDAAMFEALGELPA
TVACWCLEDDLPVLANYPADALPFISLPQHQAYLIYTSGSTGKPKGVVVSHGEIAMHCAA
VIERFGMRADDCELHFYSINFDAATERLLVPLLSGAQVVLRAQGQWDAEEICGLIRTHGI
NILGFTPSYGSQLAQWLATRQQTLPVRMCITGGEALTGEHLQRIRAAFQPQVFFNAYGPT
ETVVMPLASLAPEHLEEGAASVPIGSIIGDRVAYILDADLALVPQGATGELYVGGAGLAQ
GYHQRPGMTAERFVADPFARNGGRLYRTGDLVRQRVDGLVEYLGRIDHQVKIRGFRIELG
EIETRLLEHDAVREAVVLALDAPSGKQLVAYLVSDAEHVALRDALKAHLKAHLPDYMVPA
HLIVLDSMPLTANGKLDRRALPQPDPEANRQHYVAPRNELESTLAAIWCAVLNVQQVGLD
DNFFELGGDSILSIQVVSRARQAGIHFSPRDLFQHQTVQTLAAVATRSEQVTAEQGLLTG
SSGLTPIQHWFFDTETPNRQHWNQALVLKPLQLLDPQRLEQALLAVLEHHDALRLSFSKR
DAQWHAEHRAVPQGGVLMQAQVRDMAHCTALFTDTQRSLDLEHGPLLRALLVDGPEGQQR
LLIAIHHLVVDGVSWRVLLEDLQTVYRQLNDGQSVSLPAKTSALRDWAARLQAYAGSESL
REELSVWQHQLAGPDAALPVARPQGSLRNRDADTVSVRLDAEHTRQLLQQAPSAYRTQVN
DLLLTALARVLCRWSGHACALIQLEGHGRETLFDDIDLTRSVGWFTSAYPLRLTPQTGQG
DSIKAIKEQLRAVPHKGLGYGVLRYLADDLCKQTLAALPSAQITFNYLGQFDQSFGADAL
FHPLDESAGLAHDPDAPLPNELSVDSQVYGGELVLRWTFSRERHDQQSIHELADAYLTEL
QSLVAHCLEDDAGGLTPSDFPLAHLTQAQLDSLPIAASAIEDVYPLTPMQEGLLLHTLLE
PGTGLYYMQDRYRINSALDPERFAQAWQAVIARHEALRASFCWNVGEDMLQVIHTPGSTP
IEYLDWSDDPEDQQEPRLQALLKQEREAGFDLLNQAPFHLRLIRVGAERYWFMMSNHHIL
IDAWCRSLLMNDFFELYMALGEGRDAQLATPPRYRDYIAWLQRQNLNEARQWWQQNLQGF
ERTTPIPSDRPFLREHAGHSGGMVVGDCYTRLDARDGAQLRELAQAHQLTVNTFAQAAWA
LVLRRLSGDRDVLFGVTVAGRPVEMPEMQRTVGLFINSIALRVKLPEDGQACSVRQWLSE
LLDSNMQLREYEYLPLVTIQEHSELPKGQPLFDSLFVFENAPVEVSVLDRAQSLNATSDS
GRTHTNFPLTAVCYPGDDLGLHLSYDQRYFDETTVQGMLGEFKRLLLALVQGFQGDMADL
PLIGEQEREFLVDGCNQSEHDYPLERSYIELFEEQVAAHPQRIAASCLDQQWTYDELNRR
SNGLGHALIAAGVGLDQPVALLAERNLDLLGMIIGSFKAGAGYLPLDPGLPSQRLRSILD
LSRTPLLVCTEASREQAIELLDGFDCQLLVWEEIPARGENPGVYSAPDNLAYVIYTSGST
GLPKGVMVEQRGMLNNQLSKVPYLALSDADVIAQTASQSFDISVWQFLAAPLFGARVDIV
PNTIAHDPQGLLEHVQAQGITVLESVPSLIQGMLAQDRIGLDGLRWMLPTGEAMPPELAH
QWLQRYPEIGLVNAYGPAECSDDVAFYRVDLASTRGTYLPIGTPTDNNRLYLLDGALELV
PQGAVGELCVAGTGVGRGYVSDPLRTAPVFVPNPFGAPGERLYRTGDLARRRSDGVLEYV
GRVDHQVKIRGYRIELGEIEARLHEQPEVRDAAVGVQEGMNGKHLVGYLVAADEALNPSE
RLDRIKQRLRAELPEYMVPLHWLWLDRLPLNANGKLDRKALPALEIGQLQSQDYLAPRNE
LEATLAAIWAEVLKVERVGVQDNFFELGGHSLLATQIASRVQKTLQRDVPLRAMFECSTV
AELAEYIDGLAANEVSAEKVDRLSDLMAELEGL