Protein Info for GFF3783 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Trans-feruloyl-CoA synthase (EC 6.2.1.34)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 622 PF00501: AMP-binding" amino acids 52 to 436 (385 residues), 168.6 bits, see alignment E=9.9e-54

Best Hits

KEGG orthology group: K12508, feruloyl-CoA synthase [EC: 6.2.1.34] (inferred from 77% identity to pol:Bpro_3112)

Predicted SEED Role

"Trans-feruloyl-CoA synthase (EC 6.2.1.34)" (EC 6.2.1.34)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.2.1.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (622 amino acids)

>GFF3783 Trans-feruloyl-CoA synthase (EC 6.2.1.34) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSQNPATAARYRPLTFGVTRATLRDGDTGVHYLSAQQDLSAFPARITDRLVHWAQTRPDQ
TLFARRSKNADGSTGDWQHISFAQALDAARRIGQGLLNRGLSADKPVLILSENDLEHALL
ALGCVYAGIAYCPTSPAYSLVSQDFDKLHHVVKTLTPGLVFAADAQRYGRAMLATLGEGV
ELVTTTGSVPGRATTSFASLLATETTPAVDAAMAATGPDTITKFLFTSGSTKMPKAVINT
QRMWCANQQQMTESMPVLAENPLVLVDWLPWNHTFGGNHNVGMVLYHGGTLYIDDGKPTP
ALMAETLRNLREIAPTVYFNVPTGFEAIANAMKTDDALRKTLLSRVRMFFYAGAALAQPV
WDALHAVQEQEIGERIVMGTGLGMTESGPFGLYVTSANVKAGDLGLPTPGLELKLVDTDG
KTEVRYRGPNITPGYWRMPAETADAFDEEGFFKTGDAVKWIDETDIHQGLKFDGRIAEDF
KLATGTFVSVGPLRAKIIAAGAPYIQDVVLTGLNMKEVGAMVFPTGAVRALSGLGAEASL
HDVLNSAPVLAHFQRVVTELAKTSTGSASRIARLCLLADPPTIDRGEITDKGSINQRAVL
AHRAETVERLHADTLHAILKPE