Protein Info for GFF3745 in Variovorax sp. SCN45

Annotation: Uncharacterized UPF0721 integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 33 to 60 (28 residues), see Phobius details amino acids 72 to 94 (23 residues), see Phobius details amino acids 105 to 123 (19 residues), see Phobius details amino acids 135 to 163 (29 residues), see Phobius details amino acids 179 to 199 (21 residues), see Phobius details amino acids 204 to 220 (17 residues), see Phobius details amino acids 226 to 245 (20 residues), see Phobius details PF01925: TauE" amino acids 8 to 241 (234 residues), 117.1 bits, see alignment E=5.3e-38

Best Hits

KEGG orthology group: K07090, (no description) (inferred from 69% identity to adn:Alide_0571)

Predicted SEED Role

"membrane protein, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (246 amino acids)

>GFF3745 Uncharacterized UPF0721 integral membrane protein (Variovorax sp. SCN45)
MLFDTTLLVVAAFVAGALNAVAGGGSFLTLPALVLTGIPAVSANATGTLALLPGYIAGAW
GFRSDTQPPPGLSALTLALLCLLGGSTGAVLLLLTPDATFRRVVPWLLLLATFLFMAGPR
LALSKKPEAARPAPAMLGVFAVTAYGGYFNGGLGILLLALFGLLGQKNLHAMNGLKNQVS
ALLTLIAVSLYAWGGLIAWREASVMMGAALLGGYAGARVARRVPVVWLRRGIAATGLTMS
VLFFLR