Protein Info for GFF3736 in Pseudomonas sp. DMC3

Annotation: D-galactonate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 transmembrane" amino acids 33 to 52 (20 residues), see Phobius details amino acids 71 to 93 (23 residues), see Phobius details amino acids 105 to 128 (24 residues), see Phobius details amino acids 162 to 183 (22 residues), see Phobius details amino acids 189 to 209 (21 residues), see Phobius details amino acids 256 to 277 (22 residues), see Phobius details amino acids 294 to 318 (25 residues), see Phobius details amino acids 330 to 347 (18 residues), see Phobius details amino acids 353 to 375 (23 residues), see Phobius details amino acids 385 to 410 (26 residues), see Phobius details amino acids 417 to 439 (23 residues), see Phobius details PF07690: MFS_1" amino acids 39 to 399 (361 residues), 180.5 bits, see alignment E=2.3e-57

Best Hits

Swiss-Prot: 43% identical to DGOT_ECOL6: D-galactonate transporter (dgoT) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 96% identity to pfo:Pfl01_2236)

MetaCyc: 43% identical to D-galactonate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-16

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>GFF3736 D-galactonate transporter (Pseudomonas sp. DMC3)
MSNSHPSSATVPPVIAGARDAVSAQRLPTRRRWFMLSLLLIATIINYIDRVNISIAAPFM
AKDLGLDKIEMGLIFSAFAWTYALALVPAGFIADRFGSRFTYGVSLISWSTVTVCQGFAT
GFASLFGLRLAVGAMEAPAFPANSRAVTVWFPARERGMASSIYVCGQYLGTALFTGALLW
LATTFDWRHVFYSTGALGIVFGVLWLYLYRDPLNCKKVSQEELKYIETGGGLVKSSQERT
RFNWRQIAELFSYRQIWAICIGKFASTSALYFFLTWFPTYLIEERKLTMIKAGIFAVLPF
VGATVGILLAGIVSDLLIRRGYSMSFARKLPLVVGSMLGMSIVLVNFTDSNLICIAVLTI
AFFAQGIASSSWAAVSEVAPKELIGLTGGITSLAANIGGIVTPIVIGAIVHATGTFAYAF
WFIGGVALIGTLSYSLLLGRLYRIELKVR