Protein Info for GFF3729 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Serine protease precursor MucD/AlgY associated with sigma factor RpoE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 794 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details PF00089: Trypsin" amino acids 619 to 784 (166 residues), 44.1 bits, see alignment E=2.3e-15 PF13365: Trypsin_2" amino acids 629 to 755 (127 residues), 89 bits, see alignment E=5.4e-29

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (794 amino acids)

>GFF3729 Serine protease precursor MucD/AlgY associated with sigma factor RpoE (Hydrogenophaga sp. GW460-11-11-14-LB1)
MRFLKNGKREESAAKNGLLPAVCRLPNLLASISVLVFLSGCVTMQGPTGLVKDLTMPFGL
ASTGLSDMLSTQVRELKSLVGASKFAEADDYFNRNSDYFESRYKDSSTPLPPEFSQLSEY
VWTTRYQDKVSRATVALKSVTAIPDRAGWPALSAQVKAASIAAATLSEDRLLRLTKQGIP
QRDLLVAELARIHAMAREGKVLAVGALADDVFSTGSHEPSYVGELKIERSDFVSSGPFQQ
AAVSRIQSLSSLEETHLRAKNFTEYLSPQSKEAVDRAYVELARRQLYADGRITLEEVGAL
SSAKPPFGTSADALRSLVKIGYVDLTSASFKDRNIFDFEVSFDRDVEVAFQPATEAIFTA
SNLSQYDFVFVTDLTVAKVSREFKSKSEIKSRFQSDTRQTPNPGYVDAMTRYQTAMSQYQ
RAQISSAMPKACQGWGCVLQGLADGVQSASTRSQVEQASSALANTPQTLTVPVYAEYAYQ
AVDINAQKTAQVNYYVIDVKAGRTLKNNFTVNDQETFNVAYNVHEKDPQHSSISRNLKNE
KEVSDWEKRPISVSLSSLFSPAGLKSATQDPFQNVQAFLQTLNSRSYAAAGPTYASNSSM
TTSRTVSTQTIADERFDSVVIVRNSKATGTGFYVTPDLILTAFHVVDGNSLAEITFHDGT
KSYGRVVDHDIRLDLALVRAQTAGKPLKIHEGPLRLGETVEAIGHPKGYEFTITRGVISA
VRKQRSATIASENFVEFIQTDTPISPGNSGGPLLLKDVVIGVNDWIRVDKGSQNLNFSVS
FNEIRNYLNRFQGR