Protein Info for PS417_18890 in Pseudomonas simiae WCS417

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 transmembrane" amino acids 26 to 42 (17 residues), see Phobius details amino acids 61 to 78 (18 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 118 to 140 (23 residues), see Phobius details amino acids 152 to 175 (24 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details amino acids 255 to 277 (23 residues), see Phobius details amino acids 292 to 310 (19 residues), see Phobius details amino acids 321 to 337 (17 residues), see Phobius details amino acids 343 to 364 (22 residues), see Phobius details amino acids 375 to 398 (24 residues), see Phobius details amino acids 410 to 429 (20 residues), see Phobius details PF07690: MFS_1" amino acids 33 to 395 (363 residues), 166 bits, see alignment E=5.7e-53

Best Hits

KEGG orthology group: None (inferred from 95% identity to pfs:PFLU4260)

Predicted SEED Role

"Major facilitator family transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U422 at UniProt or InterPro

Protein Sequence (453 amino acids)

>PS417_18890 MFS transporter (Pseudomonas simiae WCS417)
MNNSSHASAAPHRDPVLARAVSKVKSHVLPLFVIMFILNYIDRVNIGFVRTHMEHDLGIG
AAAYGFGAGLFFIGYALFEVPSNMLLQKVGARLWLTRIMFTWGIVATLMAFIQNETHFYI
LRFLLGVAEAGFFPGVIYYFTRWLPGAERGKAIAIFLSGSAVASLISGPLSGALLQIEGF
GFHGWQWMFAIEGLASVALGFFVWFWLDSKPHDAQWMTREEQDALVNAIDQEQRDREALT
TVKPTLGKLLKDRQILLFCALYFCIQLTIYAATFWLPSIIKKMGDLTDVQVGFFNSIPWL
ISIIAMYAFASLSGKFKFQQAWVAAALLIAAAGMFMSTTGGPIFAFVAICFAAIGFKSAS
SLFWPIPQGYLDVRIAAAVIALINSIGNLGGFVAPTTFGFLEQTTGSIQGGLYGLAGTSL
LAAILVFFAKTSPSAVPISPSAEPTNAALSKPL