Protein Info for GFF3590 in Sphingobium sp. HT1-2

Annotation: DNA internalization-related competence protein ComEC/Rec2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 327 transmembrane" amino acids 36 to 53 (18 residues), see Phobius details amino acids 59 to 79 (21 residues), see Phobius details amino acids 86 to 107 (22 residues), see Phobius details amino acids 115 to 133 (19 residues), see Phobius details amino acids 270 to 294 (25 residues), see Phobius details amino acids 303 to 323 (21 residues), see Phobius details PF13567: DUF4131" amino acids 58 to 208 (151 residues), 60.9 bits, see alignment E=1.3e-20 PF03772: Competence" amino acids 246 to 324 (79 residues), 55 bits, see alignment E=8.1e-19

Best Hits

KEGG orthology group: K02238, competence protein ComEC (inferred from 68% identity to sjp:SJA_C1-08930)

Predicted SEED Role

"DNA internalization-related competence protein ComEC/Rec2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (327 amino acids)

>GFF3590 DNA internalization-related competence protein ComEC/Rec2 (Sphingobium sp. HT1-2)
MAFEPRQTSVGRRTVRIAHNGFARIEQWLEVEREQLALWVPVALGVGIAGWFMLPGPAQW
LACCCGALGLACLALLLPVGARLRHMLVAGGLLACVGCLLVWGKATWLGQPPLARPIFAQ
VTGTVTAVAKLPAQQMVRVGLRPIEAPVLPAAIRVNIAEADMPEGLGKGAVLRFRVRLMP
PAPPSVPGAFDFARRAYFQGVGATGRALAPVEVVEQTREGPTLRARLFDHISGQVADAPA
GIAVALATGDQGAIAEADAEAMRRSGLAHLLSISGLHVTALIGAVIFLLLRLLALIPRAA
LDWPLMLIAAAGGALAGIGYTLLTSAL