Protein Info for GFF3573 in Variovorax sp. SCN45

Annotation: Efflux ABC transporter, ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 PF00005: ABC_tran" amino acids 27 to 171 (145 residues), 115.4 bits, see alignment E=3.3e-37 PF13304: AAA_21" amino acids 140 to 200 (61 residues), 34.6 bits, see alignment E=2e-12

Best Hits

Swiss-Prot: 61% identical to NODI_PARXL: Nod factor export ATP-binding protein I (nodI) from Paraburkholderia xenovorans (strain LB400)

KEGG orthology group: K09695, lipooligosaccharide transport system ATP-binding protein (inferred from 96% identity to vpe:Varpa_5647)

Predicted SEED Role

"ABC, transporter, ATP-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>GFF3573 Efflux ABC transporter, ATP-binding protein (Variovorax sp. SCN45)
VPPTTAPTPPLFHVSRLRKRYGETTVVDDLSFEIAPGECLGVIGPNGAGKTTTIRMCLGL
TAPDGGEISALGLQMPRDALAIKAQLGVVSQFDTLDPDFSCAENLVVYGRYFGFGKAQVR
ARVPQLLEFAALSHKADAKPGELSGGMRRRLSLARALVNDPKLLLLDEPTTGLDPQARHL
MWERLQVLLQQGKSILLTTHFMDEAERLCSRLLVLDHGRKIAEGRPRDLIAEHLEPDVVE
VYGNGALSLAESAELKAMAARVEVSGETVFFYTQDARRLLEALTRHGGLRTFHRPANLED
LFLKLTGRQIREDG