Protein Info for GFF3552 in Variovorax sp. SCN45

Annotation: Hsp90xo protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 620 transmembrane" amino acids 120 to 139 (20 residues), see Phobius details PF13589: HATPase_c_3" amino acids 38 to 144 (107 residues), 34.9 bits, see alignment E=1.5e-12 PF00183: HSP90" amino acids 253 to 357 (105 residues), 36.3 bits, see alignment E=3.4e-13

Best Hits

KEGG orthology group: K04079, molecular chaperone HtpG (inferred from 59% identity to sml:Smlt1367)

Predicted SEED Role

"probable heat shock protein (hsp90 family)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (620 amino acids)

>GFF3552 Hsp90xo protein (Variovorax sp. SCN45)
MSDFPPPDLPPQTPALQTTQVHLDGLFDVLAKHLYSTPVVAIRELIQNAHDSISRRRLED
PSFTEAGRIDVLADEAAQTLVIRDNGSGLTEQELHRYLATLGNGYTRQLRASDKDGSDEL
IGLFGLGFLSAFVVAEQVLVNSTSFQSPGEGWRYRSSDGRRYAVQAIDARPVGTEIHLAM
RSDFNHLCSAGVLKKVLGRYCALLREPLWFDDECVNADAPPWRAAADGVVVHPAVLQRQR
MAFAARMERHFEPICVIPVEPEGDSDARGLLWVQDGATYGTSDNRHLSVYVRGMLLDDEA
RDLLPVWAGFIGGVIESNALTPTASREDLQRDAAYQATRAHIQDALIRGLADLSQSQAPA
WSRLLTRHNEALLGAALCEDELFTMLADAVRLPTSQGDLPVRSLVREGRIHLSLGQSGGF
EDVLFRALQVPVARGDRYAVAGFLRQWVRDRGVQLIEIGTAAGNARMFRGEDLPESELAW
LREHLAWGELVVPARFVSPELPLIAVPDREAQLKARLETDEARKRMAGAALSLARAFTQR
IDASVSARLYVNLDNPAIQALLQSHREGRAVPAHAVALLRSFKAIMAPGGEELKGQPPLV
ELLADFSQAVAALCAPRAAS