Protein Info for PS417_18035 in Pseudomonas simiae WCS417

Annotation: general secretion pathway protein GspD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 703 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR02517: type II secretion system protein D" amino acids 91 to 689 (599 residues), 458 bits, see alignment E=2.6e-141 PF21305: type_II_gspD_N0" amino acids 91 to 156 (66 residues), 34 bits, see alignment E=3.3e-12 PF03958: Secretin_N" amino acids 188 to 246 (59 residues), 35.9 bits, see alignment 1.1e-12 amino acids 253 to 318 (66 residues), 34 bits, see alignment E=4.3e-12 amino acids 328 to 440 (113 residues), 44.5 bits, see alignment E=2.2e-15 PF00263: Secretin" amino acids 514 to 679 (166 residues), 180.1 bits, see alignment E=4.4e-57

Best Hits

KEGG orthology group: K02453, general secretion pathway protein D (inferred from 85% identity to pfs:PFLU4070)

Predicted SEED Role

"General secretion pathway protein D"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UHS6 at UniProt or InterPro

Protein Sequence (703 amino acids)

>PS417_18035 general secretion pathway protein GspD (Pseudomonas simiae WCS417)
MRTSTFCLATALVLGGCGSFPDRLEPDDDLLHEAMQGTGSQRPPTEQAAAETPPPSVQPP
AQRQLIRGNQQFVRAPAAQPVAKEKGGDIVFNFADQPIEAVINSVMGDLLHENYSIAQGV
KGNVSFSTSKPVDKQQALSILETLLSWTDNAMIKQGDRYVILPANQAVAGKLVPQMNVAQ
PSSGLSARLFALRYISATEMQKLLKPFARENAFLLVDPARNVLSLAGTPDELANYQDTID
TFDVDWLKGMSVGVFGLQRASVAELMPQLQSMFGPDSGMPLAGMLRFLPIERTNSVVAIS
SQPQYLSEVGDWIRTIDEGGGNEPQMYVYDVRNMKAADLAKYLRQIYGTGAIKDDTPAKV
APGLRTTTLSSLNSGGLQNNPPAAEESEPQEKEVAPTSALEAGTRITAQKSSNQLLVRTR
PAQWKEIEAAIKRLDNPPLQVQIETRILEVKLTGELDLGVQWYLGRLAGNSSSTTVANAS
GSQGALGGGGAGLGATDSLFYSFVSSNLQVALHALETNGRTQVLSAPSLVVMNNQPAQIQ
VGDNIPINQTTVNTGDADTTLSSVEYVQTGVILDVVPRINPGGLVYMDIQQQVSDAENQS
TNSDTPVNPRISTRSVSTQVAVQSGQTVLLGGLIKQDNQESVSAVPYLGKIPGLRWLFGS
TSKSKDRTELIVLITPKVITSSGQARQVTDDYRQQMQLLRLDK