Protein Info for GFF3515 in Pseudomonas sp. DMC3

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 526 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 64 to 83 (20 residues), see Phobius details amino acids 308 to 324 (17 residues), see Phobius details amino acids 333 to 348 (16 residues), see Phobius details PF13519: VWA_2" amino acids 97 to 203 (107 residues), 58.1 bits, see alignment E=2.6e-19 PF07719: TPR_2" amino acids 410 to 442 (33 residues), 31.1 bits, see alignment (E = 3e-11) PF00515: TPR_1" amino acids 411 to 443 (33 residues), 32.7 bits, see alignment (E = 8.9e-12) PF13414: TPR_11" amino acids 417 to 455 (39 residues), 35 bits, see alignment 1.9e-12

Best Hits

KEGG orthology group: K07114, uncharacterized protein (inferred from 72% identity to pfl:PFL_2845)

Predicted SEED Role

"TPR domain protein in aerotolerance operon"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (526 amino acids)

>GFF3515 hypothetical protein (Pseudomonas sp. DMC3)
MEINLSDFHFLRPLWLLLALFGAMLPLIWRRSRDLQKRLRGDIAEHLLPHLLITPQDHQR
WRPVHLLCALLILGAIAAAGPTWEQDRPDFLENRAPLIVAVDLSPSMDANDVQPTRLEAV
KHKLHDLLQRRAAARTALIAYAGSAHLVLPPTDDPALLDSFIQALGTGLIDKPGKNVAAV
IDQAKRLLSAENTPGSLLLMTDGADTTQLDDPQKHLDGSALQVLVLAVGSEDSGVITTAS
GQPKIDSSGRPVLGSFDQAALKQLASAVDAPLGSLTLNNDDLEWIELHARQHFQSASAEQ
RELHWKDAGYWLCWPLLLLALFSVRKGWSVNWMPALFLAVGLGWPAAPAQANALTDAFFT
RDQQGRWAFEHDRLPEAAALFVDPYWKGVAAYHAADYDLAMATFARLDTPQAYFYLGNIY
VRRFKFDQAIAAYSQALKLQPQFPEASANLALAQALLKDTESAEKNAPQTKPDEVKFDKA
PGKGQSKKVETQQAASDALWLENLTTSPAKFLRQKFSLQDQQGDRP