Protein Info for PS417_17925 in Pseudomonas simiae WCS417
Annotation: acyl-CoA dehydrogenase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 72% identical to HPAH_ACIBA: p-hydroxyphenylacetate 3-hydroxylase, oxygenase component (C2-hpah) from Acinetobacter baumannii
KEGG orthology group: None (inferred from 89% identity to pfs:PFLU3290)Predicted SEED Role
"P-hydroxyphenylacetate hydroxylase C2:oxygenase component"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1N7UHQ9 at UniProt or InterPro
Protein Sequence (389 amino acids)
>PS417_17925 acyl-CoA dehydrogenase (Pseudomonas simiae WCS417) MKKPNPLLEDLKPLLPIIAANATQAEQQRQVPDENMALLKSIGLHRAFQPKAFGGLELSL PEFADCIALLAGSCASTAWAMSLLCTHSHQLALFSAQLQQEIWGENPHATASSSIAPFGR VVEGEGGVHFSGEMGWSSGCDHGEWAIVGCRRQNAEGGQDYCFAVLPRSDYQIRDDWYAA GMKGSGTKTLVIDNVWVPEHRIQKAKDMMEGKSAGFGLYPDSQIFYAPYRPYFASGFSTV SLGVAERMLEVFREKTKNRVRAYTGAAVGAATPALMRLAESTHQVAAARAFLEKTWQDHA EHSAAHRYPSRETLAFWRTNQAYATKMCIEAVDRLFAAAGGNAWFEHNEMQRLFRDSHMT GAHAYTDYDVCAQILGRELMGLEPDPSMV