Protein Info for GFF350 in Variovorax sp. SCN45

Annotation: Ferric siderophore transport system, biopolymer transport protein ExbB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 210 transmembrane" amino acids 12 to 28 (17 residues), see Phobius details amino acids 111 to 135 (25 residues), see Phobius details amino acids 158 to 180 (23 residues), see Phobius details PF01618: MotA_ExbB" amino acids 67 to 195 (129 residues), 108.4 bits, see alignment E=1.1e-35

Best Hits

KEGG orthology group: K03561, biopolymer transport protein ExbB (inferred from 97% identity to vpe:Varpa_3284)

Predicted SEED Role

"Ferric siderophore transport system, biopolymer transport protein ExbB" in subsystem Campylobacter Iron Metabolism or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (210 amino acids)

>GFF350 Ferric siderophore transport system, biopolymer transport protein ExbB (Variovorax sp. SCN45)
LFSIIVAAGWPIWPLLACSVIALALVIERFTSLKTVRVLPPKLLDETITVSQGAIPGPDV
VTKLERNSMLGQVLAAGLRALNANPRCTEDDLRAAMEASGRTVAHKLERYLPALATIASA
APLLGLLGTVIGMIEIFGSQSPGSGAVGSGNPAQLAHGISIALYNTAFGLIVAIPTLIFW
RYFRSRVDEYLLNLELSGERFARHLNALRK