Protein Info for GFF35 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Alkaline phosphatase (EC 3.1.3.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00932: LTD
  • amino acids 24 to 142 (119 residues), 63.5 bits, E=2.2e-21
• PF07589: PEP-CTERM
  • amino acids 202 to 227 (26 residues), 30.2 bits, see alignment (E = 3.4e-11)
• TIGR02595: PEP-CTERM protein-sorting domain
  • amino acids 203 to 228 (26 residues), 22.2 bits, see alignment (E = 8.7e-09)

Best Hits

KEGG orthology group: None (inferred from 60% identity to mfa:Mfla_2427)

Predicted SEED Role

"Alkaline phosphatase (EC 3.1.3.1)" in subsystem Phosphate metabolism (EC 3.1.3.1)

MetaCyc Pathways

• diethylphosphate degradation (1/2 steps found)

KEGG Metabolic Maps

• Folate biosynthesis
• gamma-Hexachlorocyclohexane degradation

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.1

Use Curated BLAST to search for 3.1.3.1

Protein Sequence (239 amino acids)

>GFF35 Alkaline phosphatase (EC 3.1.3.1) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MKKMSVLHRMLAATLLAGSALIAAPAHASVFITEFSYQSAASDEKGEYIEFTNTGLTDVD
FTGWSYDDDSRTSLTFNLSEFGIVRAGESVIVTEIDPDLFRTRWNLDSSVKVIGFMAPNF
ARADEVNLYDAQLNLVDRLTYGDNTIGGVRPRFNAARPGSFAELGQNNIHGWVLSSVGDA
DGSWTSTVGDVGSPGFSSLVTPVPEPEAYALLLAGLGIVGAAVARRRRATLPTEVPATA